Electrolyte and salivary amylase

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Discussion Overview

The discussion revolves around the activation of salivary amylase by chloride ions, specifically comparing the effects of potassium chloride (KCl) and sodium chloride (NaCl) on enzyme activity. Participants explore potential reasons for observed differences in enzyme rates in their experiments.

Discussion Character

  • Exploratory, Technical explanation, Experimental/applied

Main Points Raised

  • One participant notes that salivary amylase requires chloride ions for activation and observes higher enzyme activity with KCl compared to NaCl.
  • Another participant suggests that the difference in enzyme activity could relate to the solvation properties of KCl versus NaCl, although they acknowledge this as a speculative idea.
  • A further inquiry is made regarding whether KCl dissociates more quickly than NaCl, indicating a potential factor in enzyme activation.
  • One participant proposes checking the dissociation constants of both salts and suggests conducting an experiment with both KCl and NaCl to investigate any negative influences on the reaction from either solution.

Areas of Agreement / Disagreement

Participants express uncertainty and propose various hypotheses, indicating that there is no consensus on the reasons behind the observed differences in enzyme activity between KCl and NaCl.

Contextual Notes

Limitations include the lack of definitive experimental data comparing the dissociation rates of KCl and NaCl and the potential influence of other factors on enzyme activity that have not been explored.

Who May Find This Useful

Researchers and students interested in enzymatic activity, biochemistry, and the effects of electrolytes on enzyme function may find this discussion relevant.

oli
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i know that salivary amylase needs to be activated with chloride ions. yet from my experiment, it seems that the enzyme rate is higher when using KCl rather than NaCl. any suggestions why?
 
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Could it have to do with solvation of KCl vs NaCl? That is a very wild guess :)
 
meaning that KCl would dissociate quicker than NaCl?
 
Maybe, it might be negligible though with such ions which dissolve in water very well, but you could just look up the dissociation constants of both?

Did you try the experiment where you add both KCl and NaCl, to see if maybe there is something negatively influencing the reaction in either solutions?
 

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