What Are the Deeper Reasons Behind Aging?

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SUMMARY

The discussion centers on the deeper biological reasons behind aging, emphasizing that aging may be a programmed process rather than solely a result of cellular deterioration. Miguel from Brazil suggests that while aging is often explained through the lens of genetic mutations and cellular quality loss, evidence such as successful cloning challenges this narrative. The conversation references cloning examples, particularly Dolly the sheep, to illustrate the complexities of aging and genetic mutations. Additionally, Michio Kaku's book "Visions" is recommended for further exploration of these themes.

PREREQUISITES
  • Understanding of genetic mutations and their role in aging
  • Familiarity with cloning techniques and their implications
  • Basic knowledge of cellular biology and cell division
  • Awareness of popular science literature, specifically Michio Kaku's works
NEXT STEPS
  • Research the mechanisms of aging in cellular biology
  • Explore the implications of cloning on genetic integrity
  • Read Michio Kaku's "Visions" for insights on longevity
  • Investigate the role of DNA mutations in the aging process
USEFUL FOR

Biologists, geneticists, and anyone interested in the scientific exploration of aging and longevity, particularly those examining the intersection of genetics and cellular biology.

meucat
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Hello people

I wrote e little text to (try) explain non-expert people the reasons we age. I don't know if my point of view if correct, and so I would appreciate graduate student in genetics or biology take little time to read it and return here their comments about. I think there are more profound reasons for aging than most TV programs or books try to explain to us.

Text can be found at http://www.meucat.com/vi.html

Thanks very much

Miguel - Brazil
 
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The unobservable designer(s?) has(have?) programmed the aging process into us. That is why we grow old and die. It is programmed.
 
O Great One said:
The unobservable designer(s?) has(have?) programmed the aging process into us. That is why we grow old and die. It is programmed.
You mean genetic? Or god?
 
From your essay:

The BBC program successively demonstrated this fact using a videotape copied time and time again, until losing all its image in a videorecorder. Using the same principle, many scientists think that the aging process happens because, when cells divide (copies of the previous hroughout the time), they loose quality or 'brightness', and the organism like a whole (formed by trillons of them), begins to age and deteriorate itself.

Nevertheless, there are many facts to contradict this point of view, and one of them is the cloning of alive beings. If cells become increasily deteriorated with successive copies, how to explain that a new and young individual from cells of old individuals can be obtained?. There are cloning cases from animals who died naturally by aging (cats and dogs), even so, owners obtained 'copies' of them by cloning, again young and healthy with all their qualities.

I believe the accumulated mutations in our DNA hypothosis, has some merit. In the case of cloning from somatic tissue, there is a problem. The new young animals, also have the accumulated genetic mutations, the adult had. The don't survive very well. For example, Dolly the sheep was the first animal cloned from an adult cell. She developed a progressive lung disease at 6 years old and had to be put down (euthanized). Sheep typically live 12 years and don't develop these kinds of ailments until old age.

(see http://news.bbc.co.uk/1/hi/sci/tech/2764039.stm)

If you haven't read it yet, I would highly recommend Michio Kaku's book called Visions. The chapter titled To Live Forever, addresses this idea and quite a few others, drawing from interviews he made with many leading scientists in the field.
 

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