Extracting Drugs w/ Eppendorf Tubes

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SUMMARY

The discussion centers on the use of Eppendorf tubes for drug extraction from solvents when conical vials are unavailable. The participant expresses concern about potential solvent reactions with the polypropylene material of the Eppendorf tubes. It is confirmed that as long as the solvents used—such as Octane, Hexane, Acetone, and Ethanol—are compatible with polypropylene, the tubes are suitable for the extraction process. Links to Eppendorf's chemical compatibility resources are provided for further verification.

PREREQUISITES
  • Understanding of solvent extraction techniques
  • Familiarity with Eppendorf tubes and their properties
  • Knowledge of chemical compatibility of materials
  • Basic laboratory safety protocols
NEXT STEPS
  • Research the chemical compatibility of Eppendorf tubes with specific solvents
  • Learn about alternative extraction methods using different containers
  • Explore best practices for solvent handling in laboratory settings
  • Investigate the properties and applications of polypropylene in laboratory equipment
USEFUL FOR

Laboratory technicians, chemists, and researchers involved in drug extraction processes who require reliable container options for solvent handling.

~christina~
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I have a question as to what container I can use to do the extract a drug from a solvent layer in. (via shaking with another solvent)
The problem is that there are no conical vials in the lab and we can't borrow any.
We do have test tubes, however the covers for the test tubes leak and thus are a hazard to shake, due to the sample loss. I was thinking about using eppendorf tubes to do the extraction in since they don't leak and have a sharp tip which would work the same way a conical vial's sharp bottom.

Is this alright? I'm not sure if the solvents would react with the plastic or anything. I hope not as this is the only thing I can think of using, instead of leaky test tubes.

Thank you

edit: since most eppendorf tubes are made with polypropylene, it shouldn't react with the solvent
 
Last edited:
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What solvents are you using? As long as the solvents are compatible with the tubes, they should be ok to use.
 
Ygggdrasil said:
What solvents are you using? As long as the solvents are compatible with the tubes, they should be ok to use.
might be...
Octane, Hexane, Decane, Acetone, 1-Propanol, 2-Propanol, Ethanol, Toluene, Cyclohexane, Methanol, Heptane, Pentane, Butanol, methylene chloride.
 

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