Extracting Drugs w/ Eppendorf Tubes

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Discussion Overview

The discussion revolves around the suitability of using Eppendorf tubes for extracting drugs from a solvent layer, particularly in the absence of conical vials. Participants explore the compatibility of various solvents with the plastic material of the tubes and address concerns regarding leakage during shaking.

Discussion Character

  • Exploratory
  • Technical explanation
  • Debate/contested

Main Points Raised

  • One participant suggests using Eppendorf tubes for drug extraction due to their non-leaking design and sharp tip, which may function similarly to conical vials.
  • Another participant inquires about the specific solvents being used, noting that compatibility with the tubes is crucial for their safe use.
  • A list of potential solvents is provided by a participant, including Octane, Hexane, Acetone, and others, indicating a range of chemical properties that may affect compatibility.
  • Links to the Eppendorf website are shared, providing information on the chemical compatibility of the tubes with various solvents.

Areas of Agreement / Disagreement

Participants generally agree that Eppendorf tubes could be a viable alternative to conical vials, provided that the solvents used are compatible with the tube material. However, there is no consensus on the specific solvents or their compatibility, as this remains a point of inquiry.

Contextual Notes

Limitations include the lack of specific information on the solvents' compatibility with Eppendorf tubes, as well as the potential for varying reactions based on the solvent's chemical nature.

~christina~
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I have a question as to what container I can use to do the extract a drug from a solvent layer in. (via shaking with another solvent)
The problem is that there are no conical vials in the lab and we can't borrow any.
We do have test tubes, however the covers for the test tubes leak and thus are a hazard to shake, due to the sample loss. I was thinking about using eppendorf tubes to do the extraction in since they don't leak and have a sharp tip which would work the same way a conical vial's sharp bottom.

Is this alright? I'm not sure if the solvents would react with the plastic or anything. I hope not as this is the only thing I can think of using, instead of leaky test tubes.

Thank you

edit: since most eppendorf tubes are made with polypropylene, it shouldn't react with the solvent
 
Last edited:
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What solvents are you using? As long as the solvents are compatible with the tubes, they should be ok to use.
 
Ygggdrasil said:
What solvents are you using? As long as the solvents are compatible with the tubes, they should be ok to use.
might be...
Octane, Hexane, Decane, Acetone, 1-Propanol, 2-Propanol, Ethanol, Toluene, Cyclohexane, Methanol, Heptane, Pentane, Butanol, methylene chloride.
 

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