Factoring a constant from each row of a matrix affects its determinant, which is linear in both rows and columns. When a factor of 2 is taken from each row of the given matrix, it results in a multiplication of the determinant by 2 for each row, leading to a total factor of 16. This is because 2 raised to the power of the number of rows (4) equals 16. To maintain the determinant's value after dividing a row by 2, the entire determinant must be multiplied by 2. Therefore, the determinant reflects this adjustment, resulting in the factor of 16.