Got a first paper ready for biophysics and have few questions on what happens. 1. If a paper needs modified what kind of feedback do I get from the editor ? 2. The paper has already been stated by the editor to be suitable for the journal. If it is then rejected do I get feedback on what the reasons were ? 3. Would I be right in presuming that a rejection means there is no doubt whatsoever amongst editors and reviewers that the central hypothesis could be correct ? That is if there was any inkling that the hypothesis might be true (and presuming if it were true then it would be publication worthy) then I would be allowed the opportunity to modify the paper ?