The first successful attempt at editing human embryos in the U.S. was conducted by a research team led by Shoukhrat Mitalipov at Oregon Health and Science University, utilizing the CRISPR-Cas9 gene-editing technique. This groundbreaking study demonstrated the ability to correct the MYBPC3 mutation associated with heart disease in preimplantation embryos, achieving high targeting accuracy and avoiding mosaicism and off-target effects. The findings, published in Nature, suggest potential for safe germline editing, although ethical concerns and the need for further research remain paramount.
PREREQUISITESGeneticists, bioethicists, medical researchers, and anyone interested in the future of genetic engineering and its implications for human health.
thejosh said:In a nutshell(i have to rush to classes) what i am implying is that genes often cross over during cell division, we call this mutation and it often happens in an organism to produce variation naturally, if we venture into introducing new genes (which is what we will eventually do) new mutations might occur which could potentially disrupt the path of nature, if and when this happens we could cause our own downfall rather than fix the issue, that is one of the main issues with impeding genetic engineering.I will post more later.
evolution.berkeley.edu/evolibrary/news/070701_cheetahAs a species, cheetahs have famously low levels of genetic variation. This can probably be attributed to a population bottleneck they experienced around 10,000 years ago, barely avoiding extinction at the end of the last ice age. However, the situation has worsened in modern times.