Fractional Saturation of Hemoglobin

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SUMMARY

The fractional saturation of hemoglobin (YO2) at a venous O2 pressure of 30 torr can be calculated using the equation YO2/(1-YO2) = (pO2/p50)^n. Given that the p50 for hemoglobin is 26 torr and the Hill constant (n) is 3, the calculation yields YO2 = 0.61. This indicates that at 30 torr, hemoglobin is approximately 61% saturated with oxygen, demonstrating the relationship between partial pressure and hemoglobin saturation.

PREREQUISITES
  • Understanding of hemoglobin's oxygen-binding properties
  • Familiarity with the Hill equation and its application
  • Knowledge of partial pressure concepts in respiratory physiology
  • Basic algebra for solving equations
NEXT STEPS
  • Study the Hill equation in detail to understand its implications in biochemistry
  • Explore the physiological significance of p50 values in hemoglobin function
  • Learn about the effects of varying pO2 on hemoglobin saturation
  • Investigate the role of hemoglobin in oxygen transport and delivery in the body
USEFUL FOR

Students in physiology, biochemistry, or medicine, particularly those studying respiratory function and oxygen transport mechanisms.

catie1981
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Homework Statement



Calculate fractional saturation (YO2) for hemoglobin at venous O2 pressure (30 torr). Assume that p50 for hemoglobin is 26 torr, Hill constant is 3.



Homework Equations



YO2/1-YO2=(pO2/p50)^n

The Attempt at a Solution



(30/26)^3=1.54=(YO2/1-YO2)= 1.54 - 1.54YO2= YO2

This is pathetic. I am so mathematically retarded it hurts. How to solve for YO2...I can't seem to get it alone...why do they always play hard to get...grrr. Thanks for any help.
 
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OMG- I feel like a complete and utter idiot. I got it. *sheesh*
 

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