Hi all, It has come to my attention this article on PF (https://www.physicsforums.com/insights/can-gene-editing-eliminate-alzheimers-disease/) about a genetic approach to prevent Alzheimer's disease, based on applying gene-editing techniques on human embryos. In short (so not to be repetitive), the idea is to introduce a variant of the APP (amyloid precursor protein) gene that prevents the formation of amyloid-β-peptide aggregate in brain cells, a product of the amyloid precuror protein (you can get an in-depth explanation of how it occurs in the mentioned article). The author talks about potential prejudices (or the absence thereof) against GE humans or non-GE humans, and also the problem where the treatment remains stricted to the wealthy. However, financial resources shouldn't be a problem, should it? Considering gene flow phenomenon, wouldn't the gene pool of the local population be altered by the introduction of the desired APP gene in a few individuals? By the way, I am aware that we are quite far, both ethically and scientifically, from editing human genes. This is purely a hypothetical question. Thanks, Rafael P.S.: I created a thread to discuss it because I couldn't make a reply in the original article.