What is Gene editing: Definition and 12 Discussions

Genome editing, or genome engineering, or gene editing, is a type of genetic engineering in which DNA is inserted, deleted, modified or replaced in the genome of a living organism. Unlike early genetic engineering techniques that randomly inserts genetic material into a host genome, genome editing targets the insertions to site specific locations.

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  1. berkeman

    Medical CRISPR treatment has been greenlit in UK in global first (for sickle cell disease and beta thalassemia)

    Interesting developments; I'm not sure how controversial this is... https://www.cnn.com/2023/11/16/health/uk-casgevy-approval-crispr-gene-editing-sickle-cell-scn/index.html
  2. F

    Can current gene editing technologies reverse age related mutations?

    How can current gene editing technologies like Prime Editing can be used to reverse all age related mutations that negatively affect some type of cell like neurons?. According to this article (you need to click on the "toggle reader view" button in firefox in order to read it without registering...
  3. Ygggdrasil

    New CRISPR-based tool for find-and-replace editing of DNA

    Over the past half decade, researchers have envisioned the https://www.physicsforums.com/insights/dont-fear-https://www.physicsforums.com/insights/dont-fear-crispr-new-gene-editing-technologies-wont-lead-designer-babies/-new-gene-editing-technologies-wont-lead-designer-babies/system as a way to...
  4. Ygggdrasil

    Measuring off target mutations during CRISPR gene editing

    https://www.physicsforums.com/insights/dont-fear-https://www.physicsforums.com/insights/dont-fear-crispr-new-gene-editing-technologies-wont-lead-designer-babies/-new-gene-editing-technologies-wont-lead-designer-babies/ is a newly developed tool that allows researchers to easily make changes to...
  5. Ygggdrasil

    Medical First genetically edited human babies reportedly born

    https://apnews.com/4997bb7aa36c45449b488e19ac83e86d As detailed in the AP news story, most scientists believe the work to be unethical as the safety of the CRISPR gene editing technique used has not yet been fully established. See also...
  6. Ygggdrasil

    Medical Scientists identify major safety issue with CRISPR

    https://www.physicsforums.com/insights/dont-fear-https://www.physicsforums.com/insights/dont-fear-crispr-new-gene-editing-technologies-wont-lead-designer-babies/-new-gene-editing-technologies-wont-lead-designer-babies/provides scientists with an easy way to introduce targeted genetic changes to...
  7. MrGenetic

    Gene Manipulation / Transformation

    Hi. If we want cell to accept vector dna in transformation, we treated with calcium chloride or chilled on ice etc.. But i have a trouble with one issue about that. Books say that ; We must choose the vector that specific according to the cell that will do transformation. But we will treat with...
  8. Ygggdrasil

    Medical Using CRISPR to cut HIV out of infected cells

    A major impediment to curing patients with HIV is the fact that the virus integrates its DNA into the genome of the cells it infects. While antiretroviral drugs and therapies can prevent infection of new cells and kill cells that are actively producing virus, a "latent reservoir" remains that...
  9. rfranceschetti

    Medical Gene flow in hypothetical genetically engineered humans

    Hi all, It has come to my attention this article on PF (https://www.physicsforums.com/insights/can-gene-editing-eliminate-alzheimers-disease/) about a genetic approach to prevent Alzheimer's disease, based on applying gene-editing techniques on human embryos. In short (so not to be...
  10. Ygggdrasil

    Medical National Academies Recommendations on Human Gene Editing

    This week on, Feb 14, the US National Academy of Sciences and National Academy of Medicine released a report giving recommendations on how...
  11. 1oldman2

    Medical China begins gene editing trial

    I came across this article, thought it was worth mentioning. http://www.nature.com/news/crispr-gene-editing-tested-in-a-person-for-the-first-time-1.20988 A Chinese group has become the first to inject a person with cells that contain genes edited using the revolutionary CRISPR-Cas9 technique...
  12. Ygggdrasil

    Insights Can Gene Editing Eliminate Alzheimer's Disease? - Comments

    Ygggdrasil submitted a new PF Insights post Can Gene Editing Eliminate Alzheimer's Disease? Continue reading the Original PF Insights Post.