How Does Bayesian Reasoning Affect Mental Disorders?

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Discussion Overview

The discussion revolves around the application of Bayesian reasoning in the context of mental disorders, exploring the implications of assigning prior probabilities to hypotheses and the role of models in scientific inference. Participants engage with theoretical aspects of Bayesian statistics and its relevance to understanding mental health conditions.

Discussion Character

  • Exploratory
  • Technical explanation
  • Debate/contested

Main Points Raised

  • Some participants express uncertainty about how to assign a priori probabilities (P(H)) to hypotheses, suggesting that there may be only a limited number of testable hypotheses at any time.
  • Others propose that while there should be a basis for assigning priors, it is not explicitly included in the mathematical framework of Bayesian reasoning.
  • A participant raises a distinction between different types of hypotheses, questioning how to assign priors to law-like hypotheses such as Newton's law of gravity or the hypothesis that AIDS is caused by HIV.
  • There is a discussion about the role of the model (M) in Bayesian inference, with some suggesting that it should include prior information about parameters relevant to observations.
  • One participant questions the implications of observations that do not align with the underlying theory, asking what P(O|M) would be in such cases.
  • Another participant notes that low posterior probabilities for model parameters indicate a need to reconsider the model or include additional parameters.
  • A later reply introduces a connection between Bayesian reasoning and mental illness, referencing an article that discusses this relationship.

Areas of Agreement / Disagreement

Participants do not reach a consensus on how to assign prior probabilities or the implications of Bayesian reasoning for mental disorders, with multiple competing views and uncertainties remaining throughout the discussion.

Contextual Notes

Limitations include the lack of clarity on how to define and assign prior probabilities, the dependence on specific definitions of hypotheses and models, and unresolved questions regarding the implications of observations that do not fit established models.

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This series really is phenomenal!
 
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I second Greg's comment.

But it occurred to me that we really have no basis at all for assigning [itex]P(H)[/itex], the a priori probability of a hypothesis. I suppose that at any given time, there are only a handful of hypotheses that have actually been developed to the extent of making testable predictions, so maybe you can just weight them all equally?
 
stevendaryl said:
I second Greg's comment.

But it occurred to me that we really have no basis at all for assigning [itex]P(H)[/itex], the a priori probability of a hypothesis. I suppose that at any given time, there are only a handful of hypotheses that have actually been developed to the extent of making testable predictions, so maybe you can just weight them all equally?

In the article, it's not [itex]P(H)[/itex] but [itex]P(H | \mathcal{M})[/itex], but I'm not sure that I understand the role of [itex]\mathcal{M}[/itex] here.
 
stevendaryl said:
I second Greg's comment.

But it occurred to me that we really have no basis at all for assigning [itex]P(H)[/itex], the a priori probability of a hypothesis. I suppose that at any given time, there are only a handful of hypotheses that have actually been developed to the extent of making testable predictions, so maybe you can just weight them all equally?

There should be a basis for assigning the prior. It's just not part of the math.

You could collect data that 1% of the population has AIDS. That would be your prior for an individual having the condition.
 
Hornbein said:
There should be a basis for assigning the prior. It's just not part of the math.

You could collect data that 1% of the population has AIDS. That would be your prior for an individual having the condition.

Okay, I was thinking of a different type of "hypothesis": a law-like hypothesis such as Newton's law of gravity, or the hypothesis that AIDS is caused by HIV. I don't know how you would assign a prior to such things.
 
stevendaryl said:
In the article, it's not [itex]P(H)[/itex] but [itex]P(H | \mathcal{M})[/itex], but I'm not sure that I understand the role of [itex]\mathcal{M}[/itex] here.
You can think of the hypothesis as being the value of a certain parameter, like the curvature of the universe. The model is the underlying theory relating that parameter to the observation, and should include prior information like the range of the parameter.
 
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bapowell said:
You can think of the hypothesis as being the value of a certain parameter, like the curvature of the universe. The model is the underlying theory relating that parameter to the observation, and should include prior information like the range of the parameter.

Suppose we observe something that is totally unrelated to the underlying theory. What is M in that case? What is P(H|M) in that case?

Edit: I should have asked what is P(O|M) in that case?
 
M can be thought of as the underlying theory, which in practice is a set of equations relating the observable quantities to a set of parameters (together with constraints on those parameters, like the ranges of permitted values). If an observation is made that is not well-accommodated by the model M, then we will find low posterior probabilities for the parameters of the model, p(H|O). This is a signal that we either need to consider additional parameters within M, or consider a new M altogether.
 
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