To calculate enthalpy change (ΔH) using specific heat capacity and mass, the formula Q = mcΔT is utilized, where Q represents enthalpy change, m is mass, c is specific heat capacity, and ΔT is the change in temperature. In the example discussed, a metal's temperature drop indicates an endothermic reaction, and the heat gained by the metal equals the heat lost by the water. It is crucial to maintain the correct signs when applying the formula, as heat gained by one component is equal in magnitude but opposite in sign to the heat lost by another. The final temperature of the system must be clarified, as it affects the calculations for ΔT. Ultimately, by equating the heat gained and lost, one can solve for the unknown temperature changes and calculate ΔH accurately.