How would I find a UV-VIS spectra of human urine?

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Discussion Overview

The discussion revolves around finding UV-VIS absorbance spectra of human urine, including the challenges and methods associated with obtaining such data. Participants explore both theoretical and practical aspects of measuring and interpreting these spectra.

Discussion Character

  • Exploratory
  • Technical explanation
  • Debate/contested
  • Experimental/applied

Main Points Raised

  • One participant expresses a desire to find existing UV-VIS absorbance spectra of urine, noting previous findings related to deep UV and fluorescence peaks.
  • Another participant suggests that obtaining the spectra can be done using a spectrometer, emphasizing the need to follow the manual and conduct the experiment.
  • A participant mentions the high cost of using a spectrophotometer as a barrier to conducting the experiment themselves.
  • One participant plans to visit a university library to search for relevant literature on the topic.
  • Another participant expresses interest in the findings and notes that understanding the fluorescences and absorptions is important, although access to instruments is necessary for practical application.
  • A participant shares a specific wavelength (450nm) where bilirubin absorbance peaks, linking it to the coloration of urine.
  • A link to a journal article is provided, suggesting that diazo compounds exhibit strong UV-VIS absorbances and noting the variability of urine spectra based on diet and individual differences. The potential for using urinary spectra in disease diagnosis is mentioned, though uncertainty remains about its current practice.

Areas of Agreement / Disagreement

Participants do not reach a consensus on the availability of UV-VIS spectra for urine or the practicality of obtaining them. Multiple viewpoints are presented regarding the methods and implications of measuring these spectra.

Contextual Notes

The discussion highlights limitations such as the dependence of urine composition on dietary intake, which may affect the spectra. There is also uncertainty regarding the diagnostic use of urinary spectra in clinical practice.

Who May Find This Useful

Researchers and students interested in analytical chemistry, biomedical diagnostics, or those studying the properties of biological fluids may find this discussion relevant.

lostminty
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Preferably I would like to find a UV-VIS absorbance spectra of urine.

I have found ones that focus on the deep UV range, and one that had fluorescence peak information.

Any help would be appreciated.
 
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Same way you take the absorbance spectra of any other sample. Get a spectrometer, read the manual, do the experiment.
 
That is my plan B. But a spectrophotometer costs 125NZD/hour :(
 
going to the uni library to look in their volumes tomorrow morning
 
Let us know the answer. It is interesting to know, and what these fluorescences/absorbtions are due to, though till you have instrument access you will not be able to use if for anything.
 
ok :)
 
found something useful, for me at least. 450nm. Where Bilirubin absorbancy peaks. Bilirubin giving urine its hue.
 
http://jb.oxfordjournals.org/content/116/2/298.short you'd likely find something like this. Diazo compounds give strong uv-vis absorbances. You'd likely end up with a huge mess of peaks with some identifiable and most others not. What is in urine is highly dependent upon food intake, so the spectra would vary widely from person to person and day to day. There is the potential for diagnosis of diseases through urinary spectra, but I'm not sure whether that's a practiced method anywhere yet. I saw a couple of papers that used HPLC with UV spec to determine if specific compounds were present in urine, but i wouldn't expect an overall spectral determination to yield clear data.
 
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