In classical mechanics, inertial frames are defined relative to an absolute rest frame, while non-inertial frames are those that accelerate with respect to it. In special relativity (SR), there is no absolute rest frame, leading to questions about why some frames are considered inertial and others not. Acceleration is absolute and can be measured, distinguishing inertial from non-inertial frames, but this raises the question of the reference frame for such measurements. The discussion highlights the ambiguity in identifying inertial frames in the absence of an absolute reference and suggests that general relativity (GR) may provide clarity by linking inertial frames to mass distribution in the universe. The conversation ultimately emphasizes the complexity of defining inertial frames within the frameworks of classical physics, SR, and GR.