yes, it really does depend on what you will leverage from your network. If it is just access the internet, then it's plug and *pray* if you need to access files between the workstations, then you again need to decided on an appropriate Protocol, for example SMB. If you need to Authenticate against a Direction, you again need to use a compatible protocol.
The problem with these big computer companies is they prefer not to use standards, and thus create problems for compatibility, especially Microsoft.
Ranger you will need a higher level protocol to 'talk' between 2 OS's than TCP/IP. Most will use IP for addresses, and perhaps TCP for Windowing and transport, but you will need something like SMB or Telnet or whatever for the actual communication.