Magnesium bisglycinate + citric acid = ?

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Discussion Overview

The discussion revolves around the interaction between magnesium bisglycinate and citric acid in a water solution. Participants explore the chemical changes that may occur, the implications of mixing supplements, and the potential formation of magnesium citrate.

Discussion Character

  • Exploratory, Technical explanation, Debate/contested

Main Points Raised

  • One participant questions what happens when magnesium bisglycinate and citric acid are mixed in water, specifically whether magnesium changes form.
  • Another participant suggests that mixing these substances could lead to the formation of magnesium citrate, which is known to have laxative properties, cautioning against mixing supplements and chemicals due to potential interactions.
  • A third participant notes that magnesium citrate itself is also a supplement that can have laxative side effects.
  • One participant proposes that magnesium bisglycinate acts as a weak base in solution, leading to an equilibrium involving glycine and magnesium citrate, while asserting that magnesium remains as Mg2+ and does not change form.
  • This participant also states that in the presence of a strong acid like H2SO4, magnesium bisglycinate would convert to glycine and MgSO4.

Areas of Agreement / Disagreement

Participants express differing views on the implications of mixing magnesium bisglycinate and citric acid, particularly regarding the formation of magnesium citrate and the potential effects of such a mixture. The discussion remains unresolved with multiple competing perspectives.

Contextual Notes

There are assumptions regarding the behavior of magnesium bisglycinate in solution and the effects of mixing with citric acid that are not fully explored. The discussion does not clarify the specific conditions under which these reactions occur.

ivannovak
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Hello,
I have a question or two that I need help with:
What happens when you put magnesium bisglycinate and citric acid into water solution?
Does magnesium change form here?

Kind regards,
IN
 
Chemistry news on Phys.org
You can get magnesium citrate (citrate of magnesia, a laxative)
Magnesium bisglynate is used as a supplement for patients with low serum magnesium levels, and sometimes as an antacid to treat acid burps for example.

The reason I mention this is that you should not fool around with mixing supplements and other chemicals because they can interact. This example turns a supplement into a laxative. Not a good idea.
 
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Likes   Reactions: berkeman and BillTre
Well technically, magnesium citrate is also a supplement with laxative side effects
 
Magnesium bisglycinate is presumably a weak base (pKa similar to other carboxylates). So in solution, you would get an equilibrium between glycine (conjugate acid of glycinate) and magnesium citrate.

Magnesium exists as Mg2+ and it wouldn't change. Even in the presence of a strong acid such as H2SO4, you would just get a full conversion of magnesium bisglycinate to glycine and MgSO4.
 

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