Magnesium bisglycinate + citric acid = ?

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Mixing magnesium bisglycinate with citric acid in water results in a chemical reaction that can produce magnesium citrate, which is known for its laxative effects. Magnesium bisglycinate is primarily used as a supplement for individuals with low magnesium levels and can also serve as an antacid. The interaction between these compounds can lead to unintended consequences, such as converting a supplement into a laxative. In solution, magnesium remains in the form of Mg2+, and the equilibrium involves glycine and magnesium citrate. Even in the presence of strong acids, magnesium bisglycinate would convert to glycine and magnesium sulfate, but the magnesium ion itself does not change form. Caution is advised when mixing supplements and other chemicals due to potential interactions.
ivannovak
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Hello,
I have a question or two that I need help with:
What happens when you put magnesium bisglycinate and citric acid into water solution?
Does magnesium change form here?

Kind regards,
IN
 
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You can get magnesium citrate (citrate of magnesia, a laxative)
Magnesium bisglynate is used as a supplement for patients with low serum magnesium levels, and sometimes as an antacid to treat acid burps for example.

The reason I mention this is that you should not fool around with mixing supplements and other chemicals because they can interact. This example turns a supplement into a laxative. Not a good idea.
 
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Likes berkeman and BillTre
Well technically, magnesium citrate is also a supplement with laxative side effects
 
Magnesium bisglycinate is presumably a weak base (pKa similar to other carboxylates). So in solution, you would get an equilibrium between glycine (conjugate acid of glycinate) and magnesium citrate.

Magnesium exists as Mg2+ and it wouldn't change. Even in the presence of a strong acid such as H2SO4, you would just get a full conversion of magnesium bisglycinate to glycine and MgSO4.
 
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