Meiosis in cell with odd diploid number

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The discussion centers on the implications of meiosis in a cell with an odd diploid number of 2n=15. Participants concluded that during meiosis, the odd number of chromosomes would lead to an unequal distribution, resulting in cells with 7 and 8 chromosomes after Meiosis I, and ultimately producing four cells with either 7 or 8 chromosomes. This scenario is indicative of aneuploidy, which often results from nondisjunction and is associated with infertility and various genetic disorders, such as Down's syndrome and Turner’s syndrome.

PREREQUISITES
  • Understanding of meiosis and its stages (Meiosis I and Meiosis II)
  • Knowledge of aneuploidy and its implications in genetics
  • Familiarity with genetic disorders related to chromosomal abnormalities
  • Basic concepts of diploid and haploid cell structures
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  • Research the mechanisms of nondisjunction in meiosis
  • Study the genetic implications of aneuploidy in human genetics
  • Explore the characteristics and effects of Turner’s syndrome
  • Investigate the relationship between chromosomal abnormalities and fertility issues
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Genetics students, biologists, and healthcare professionals interested in understanding chromosomal abnormalities and their effects on reproduction and genetic disorders.

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I've come across a question which is asking what would happen in a cell with odd diploid number 2n=15 when it undergoes meiosis. Here's my thinking:
- 15 chromosomes, so 7*2 homologues + 1 loner?
- Hence, after Meiosis I, we'd have 7 chromosomes in one cell, and 8 in the other?
- After meiosis II, we'd have 2 cells with 7 chromosomes, and 2 cells with 8?

Just wanted to check that this is a plausible answer for this situation? It seems a bit rare, and odd 2n appears to be associated with infertility (e.g. mules).

Would appreciate a confirmation of this :) Thanks!
 
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An odd number of chromosomes is often the result nondisjunction...the chromosomes don't separate properly. The term aneuploidy is used for such an abnormal number of chromosomes. Many genetic disorders are associated with odd numbers of chromosomes. Down's syndrome in humans for example...but there are also examples of people who have extra sex chromosomes who live normal lives...XXY trisomy for example.
 
@Megaquark is correct - that example is NOT diploid. And since you see why meiosis has problems, aneuploid organisms, if they live long enough to attempt reproduction, have serious issues with fertility. They cannot create viable gametes generally.
 

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