Non-Vital Biological Functions of Elements

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Discussion Overview

The discussion revolves around the non-vital biological functions of elements, particularly focusing on lithium and its presence in organisms. Participants explore the implications of trace elements in biology, questioning what constitutes a non-vital function and whether other elements exhibit similar characteristics.

Discussion Character

  • Exploratory
  • Debate/contested
  • Technical explanation

Main Points Raised

  • Some participants note that lithium is present in trace amounts in all organisms but serves no apparent vital biological function, raising questions about potential non-vital roles.
  • Others reference articles suggesting that lithium may have non-vital functions, although these are not clearly defined.
  • One participant mentions that many substances, including drugs, can have biological effects without being vital, citing lithium's use in psychiatric medicine.
  • Another participant discusses strontium's presence in human bones and its chemical similarity to calcium, suggesting it may have non-vital biological roles.
  • Concerns about trace elements being treated as ultratrace elements in nutrition are raised, with examples like silicon and silver being mentioned for their ambiguous biological roles.
  • Some participants express uncertainty about the biological functions of various elements, indicating that many have not been thoroughly studied, particularly in plant physiology.
  • Discussion includes references to agricultural studies on micronutrients, particularly selenium, and its essential role in livestock health.

Areas of Agreement / Disagreement

Participants do not reach a consensus on the specific non-vital functions of lithium or other elements. Multiple competing views and uncertainties about the biological roles of various trace elements remain evident throughout the discussion.

Contextual Notes

Limitations include the lack of clear definitions for non-vital functions, the difficulty in detecting low levels of trace elements, and the ongoing research into the biological roles of various elements.

Drakkith
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I was reading the wikipedia article on Lithium and noticed that it says:

Trace amounts of lithium are present in all organisms. The element serves no apparent vital biological function, since animals and plants survive in good health without it, though non-vital functions have not been ruled out.

I'm just curious as to what sort of non-vital functions they might be referring to. Do other elements or chemicals have non-vital biological functions?

Thanks.
 
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Drakkith said:
I was reading the wikipedia article on Lithium and noticed that it says:

Trace amounts of lithium are present in all organisms. The element serves no apparent vital biological function, since animals and plants survive in good health without it, though non-vital functions have not been ruled out.

I'm just curious as to what sort of non-vital functions they might be referring to. Do other elements or chemicals have non-vital biological functions?

Thanks.
I'm sure there is more to it than the Wiki article mentions, take a look at this article. (not sure if Psych today is an approved source but it may be relevant)
.

https://www.psychologytoday.com/blo...atry/201201/could-you-have-lithium-deficiency
 
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Here's an interesting article published by UC Davis:
1.8 Essential Elements for Life
...
The Trace Elements
Because it is difficult to detect low levels of some essential elements, the trace elements were relatively slow to be recognized as essential. Iron was the first. In the 17th century, anemia was proved to be caused by an iron deficiency and often was cured by supplementing the diet with extracts of rusty nails. It was not until the 19th century, however, that trace amounts of iodine were found to eliminate goiter (an enlarged thyroid gland). This is why common table salt is “iodized”: a small amount of iodine is added. Copper was shown to be essential for humans in 1928, and manganese, zinc, and cobalt soon after that. Molybdenum was not known to be an essential element until 1953, and the need for chromium, selenium, vanadium, fluorine, and silicon was demonstrated only in the last 50 years. It seems likely that in the future other elements, possibly including tin, will be found to be essential at very low levels.
I interpret that as "They are still figuring it out".
From the periodic table they display, lithium is labeled: Nonessential for humans

I also found lots of fun articles on "lithium":

A Negative Association Between Lithium in Drinking Water and the Incidences of Homicides, in Greece
:oldsurprised:
hmmm... Lithium may not be essential for you, but the people around you might survive longer if you're not deficient. :oldbiggrin:
 
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There are certainly many substances that are not vital to the human body but still have biological effects on the body. For example, drugs, both legal and illegal, have a variety of effects on the body. Lithium in particular has some uses in psychiatric medicine.
 
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Slightly different point -
A stable Strontium isotope, outside of medical applications, may be found in human bone, especially in areas where the element occurs in deposits. It is apparently harmless in small quantities. The way I used to explain this: in food and water there can be tiny amounts of oddball impurities, like strontium. The strontium atom is chemically very similar to calcium, so your biological metabolic pathways treat it like calcium. It gets parked in bone, for instance.

Also note that trace amounts of some elements get relegated to the "outbound biological highway": growing hair follicles. Which gets the element out the way biologically. Fat is also a dumping ground for toxins. Argyria is an example.

Some elements are so ubiquitous and occur in tiny, tiny amounts that AFAIK some are still labelled 'ultratrace' elements in nutrition:
http://www.annualreviews.org/doi/abs/10.1146/annurev.nu.04.070184.000321

Silicon example: it is REALLY difficult to get every single silicon atom out of water and food for animals, so silicon dietary requirements have not been determined for humans or livestock.

And then there is silver: https://en.wikipedia.org/wiki/Argyria Blue aliens in the movies have nothing on people who take lots of colloidal silver, for example.
 
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jim mcnamara said:
And then there is silver: https://en.wikipedia.org/wiki/Argyria Blue aliens in the movies have nothing on people who take lots of colloidal silver, for example.

Oh god! That's crazy!
 
Drakkith said:
I was reading the wikipedia article on Lithium and noticed that it says:

Trace amounts of lithium are present in all organisms. The element serves no apparent vital biological function, since animals and plants survive in good health without it, though non-vital functions have not been ruled out.

I'm just curious as to what sort of non-vital functions they might be referring to. Do other elements or chemicals have non-vital biological functions?

Thanks.

Several elements have no known biological function:

http://scienceblogs.com/startswithabang/files/2013/06/daves-elements.jpg

As for Lithium, it does appear to have a biological function (I don't know about 'vital', tho):

http://link.springer.com/book/10.1007/978-1-4612-3324-4

Most of the elements I looked up seem to be better studied in plant physiology, of which I know nothing.

This article seems worthwhile:

http://www.encyclopedia.com/topic/Trace_Elements.aspx
 
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@Andy Resnick - Agriculture colleges have studied micronutrients in livestock extensively. Example: selenium

The story I got was pig farmers in some regions of the US state Iowa were having issues with growing pigs. The Ag college folks saw the Schwarz paper, and they worked through a lot of issues. That spread throughout the animal husbandry researchers.

Really interesting history - https://www.asas.org/docs/publications/oldfieldhist.pdf?sfvrsn=0
 
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jim mcnamara said:
@Andy Resnick - Agriculture colleges have studied micronutrients in livestock extensively. Example: selenium

Selenium is interesting- it is an essential nutrient in our (mammalian) cell culture media. The amino acid it forms, selenocysteine, was discovered in the 1970's:

https://en.wikipedia.org/wiki/Selenocysteine
 
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