Partition Function of a brain tumor

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Discussion Overview

The discussion revolves around finding the partition function of a brain tumor that has magnetic nanoparticles injected into it, particularly in the context of measuring temperature under an external alternating magnetic field. The scope includes theoretical approaches, experimental techniques, and potential applications in medical physics.

Discussion Character

  • Exploratory
  • Technical explanation
  • Conceptual clarification
  • Debate/contested

Main Points Raised

  • One participant is seeking guidance on how to find the partition function for a complex system involving a brain tumor and magnetic nanoparticles, expressing uncertainty about techniques applicable to such systems.
  • Another participant questions whether the original inquiry pertains to the partition coefficient, which relates to the concentration ratios inside and outside the tumor.
  • A participant clarifies their intent to find the temperature of the tumor-MNP system, suggesting that the partition function could help derive thermodynamic variables, while acknowledging the system may not be in thermal equilibrium.
  • One participant mentions various methods for measuring temperature in vivo, including the use of CT scanners, providing a reference link for further reading.

Areas of Agreement / Disagreement

Participants express different interpretations of the initial question, with some focusing on the partition function and others suggesting the partition coefficient. The discussion remains unresolved regarding the best approach to find the temperature of the system and the relevance of the partition function in this context.

Contextual Notes

There are limitations in the information available, including the lack of details on the system's thermal equilibrium and the specific techniques for calculating the partition function in this complex scenario.

eprparadox
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Hello!

I'm just beginning some volunteer research work on a project and I've been tasked with finding the partition function of a brain tumor that has magnetic nanoparticles injected into it. CT scans provide concentrations and distributions of the magnetic nanoparticles, but I'm quite lost on how to actually find the partition function!

It seems that my course work has only taught me how to find the partition function for simple systems and I don't really know where to start looking for techniques on finding the partition function for complex systems such as this.

If anyone has some insight or could lead me to some academic papers I could read to get started that would be great.

Thank you so much.
 
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Do you mean partition coefficient (as in ratio of concentrations inside of the tumor and outside of the tumor)?
 
Hmm...maybe I jumped the gun. I'll back up a bit:

We have this tumor injected with magnetic nanoparticles (MNP) and will be heated up by an external alternating magnetic field. We have the concentration and distribution of the MNPs and we're looking for the temperature of the tumor. Now I'm assuming this is the temperature as a function of the alternating magnetic field but I don't have a ton of information and won't until Thursday. I just wanted to go in with some sense of a good approach.

I thought finding the partition function of the tumor+MNP system would allow me to then find any thermodynamic variable, including temperature. Thats why I thought the Partition Function would be good to find. But we also don't necessarily have a system in thermal equilibrium.

But then my question then comes to: how might I go about finding the temperature of this system?

Thanks again!
 

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