Protein structure drawing method

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Discussion Overview

The discussion centers around the naming and classification of a specific method for drawing protein and RNA structures, particularly focusing on the representation of secondary structures. Participants explore how these structures are visually represented and the terminology used to describe them.

Discussion Character

  • Conceptual clarification
  • Debate/contested

Main Points Raised

  • John seeks the proper name for the method of flattening protein and RNA structures to clarify the amino acid sequence and overall structure.
  • Some participants suggest terms like "secondary structure diagram," "flattened secondary structure," or "2D secondary structure" but note that there may not be a universally accepted name.
  • One participant mentions that for nucleic acids, the term "stem-loop diagrams" is sometimes used, while for proteins, "secondary structure diagram" is more common.
  • John expresses admiration for the aesthetic qualities of these drawings, comparing their complexity and beauty to street maps.

Areas of Agreement / Disagreement

Participants generally agree that the drawings are referred to as secondary structure representations, but there is no consensus on a specific name for the flattening method used.

Contextual Notes

There is uncertainty regarding the terminology and whether a specific name exists for the flattening method. The discussion reflects varying experiences and interpretations among participants.

Who May Find This Useful

Individuals interested in biochemistry, molecular biology, or structural biology may find this discussion relevant, particularly those exploring the visualization of protein and RNA structures.

John37309
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Protein structure drawing method

I want to know the proper name given to this particular method of drawing proteins, RNA and Genes. I have two examples;

If you look at the Wikipedia page for tRNA, they show the Tertiary structure of tRNA like this;

220px-TRNA-Phe_yeast_1ehz.png


http://en.wikipedia.org/wiki/Transfer_RNA

But they also show this particular type of secondary tRNA structure;

220px-TRNA-Phe_yeast_en.svg.png


I personally describe this method as flattening out the structure so we can see the exact amino acid sequence more clearly. Wikipedia describes this structure for tRNA as the "Secondary cloverleaf structure". But they only say that because tRNA looks like a three leaf clover when you flatten it out like that. Other proteins and stuff take on very different patterns when you flatten them out!

The same flattening method is used here for the Gene HAR1F;
http://en.wikipedia.org/wiki/HAR1F

I want to know what is the proper name given to this flattening method of drawing proteins, amino acids and genes?

John.
 
Last edited:
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I don't know if there's a specific name, but it'd call it a secondary structure diagram. These types of images are meant to represent the secondary structure (e.g. the base pairing for RNAs or the alpha-helices/beta-sheets for proteins), but do not accurately represent the tertiary structure (the overall 3D folding) of the molecules.
 
Thanks Ygggdrasil,
So your not aware of any specific name given to this particular drawing method other than just "secondary structure" or maybe "flattened secondary structure" or maybe "2D secondary structure".

OK, Thank you,
John.
 
For nucleic acids (especially RNA), I've heard them referred to as stem-loop diagrams.

For proteins, it's usually just "secondary structure diagram" in my experience.
 
Thanks Mike,
Yes, that seems to be the case here. People just seem to be referring to these drawings as secondary structure.

These drawings are beautiful, they have an hypnotic effect on my mind. Some of them become very large and very complex. But the more complex they get, the more beautiful they look. The look like street maps for living things! stunning! Shockingly beautiful! It reminds me of the London underground maps :)

16S rRNA Secondary Structure

rrna.gif


John.
 
Last edited:

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