Question about the synthesis of fatty acids

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SUMMARY

The synthesis of fatty acids involves the repetition of a cycle seven times to produce a 16-carbon chain, primarily utilizing acetyl-CoA as the carbon source. However, one carbon in odd-chain fatty acids, such as C15 or C17, originates from propionyl-CoA instead of acetyl-CoA. This distinction is crucial for understanding the biochemical pathways involved in fatty acid synthesis.

PREREQUISITES
  • Understanding of fatty acid synthesis pathways
  • Knowledge of acetyl-CoA and propionyl-CoA roles in metabolism
  • Familiarity with even- and odd-chain fatty acids
  • Basic biochemistry concepts related to carbon chain elongation
NEXT STEPS
  • Study the biochemical pathways of fatty acid synthesis in detail
  • Learn about the role of propionyl-CoA in odd-chain fatty acid metabolism
  • Explore the differences between even- and odd-chain fatty acids
  • Investigate the implications of fatty acid chain length on biological functions
USEFUL FOR

Biochemists, molecular biologists, and students studying metabolic pathways will benefit from this discussion, particularly those focusing on lipid metabolism and fatty acid biosynthesis.

samy4408
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Hello , in the course of fatty acids synthesis the professor said that after the repetition of the cycle 7 times we end up with a 16 carbon chain
and he added that all the carbons came from acetyl-COA except for one .
i didn't understand the last one , what is the carbon that don't come from acetyl-COA ?
 
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In even-chained fatty acids, this also is from AcCoA.
In odd-chained (e.g. C15 or C17), however, the initial element is Propionyl-CoA.

HTH
 
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Likes   Reactions: jim mcnamara and samy4408
thanks a lot !
 

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