Taking Pills with Food/Water: Why and How?

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SUMMARY

This discussion focuses on the necessity of taking certain medications with food or water to enhance absorption and minimize stomach upset. Key reasons include the potential for stomach irritation when medications are taken on an empty stomach and the improved absorption of fat-soluble compounds when consumed with food. Additionally, some medications may interact negatively with specific foods, such as dairy products, which can hinder their effectiveness. Understanding these factors is crucial for proper medication management.

PREREQUISITES
  • Understanding of pharmacokinetics and drug absorption
  • Knowledge of medication interactions with food
  • Familiarity with fat-soluble and water-soluble vitamins
  • Basic principles of gastrointestinal physiology
NEXT STEPS
  • Research the effects of food on drug absorption and efficacy
  • Learn about enteric-coated medications and their mechanisms
  • Investigate specific medication-food interactions, particularly with dairy
  • Explore the role of stomach hormones in drug absorption
USEFUL FOR

This discussion is beneficial for healthcare professionals, pharmacists, and patients seeking to understand the optimal conditions for medication intake to ensure effectiveness and reduce side effects.

Mk
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Why do I need to take some pills with food or water? Are they too strong for the stomach or something? How? All that hydrochloric acid in there doesn't eat through.
 
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Some medicines will make you feel ill unless taken with food, but will otherwise still work properly. On the other hand, some foods can actually prevent the absorption of some medicines. Some medicines cannot be taken with milk, for example.

- Warren
 
There are two reasons:
1) the medicine can cause a stomach upset if you take it without food.
2) food will make the medicine be absorbed better into the body.

Some medications are absorbed better without food, so you need to follow what the prescription says. One example would be that the medication reacts with something in food, an other example is that the medication has an enteric coating that does not dissolve until it gets into the intestine (the presence of food will make the uptake slower).
 
Are there some hormones released when the stomach is fuller that allow for better absorption?
 
It are the fat-soluble compounds that are better absorped when taken with food.
 
Monique said:
It are the fat-soluble compounds that are better absorped when taken with food.
u can swallore some lemon to reduce fat. I heard some people does it
 
Rotan72 said:
u can swallore some lemon to reduce fat. I heard some people does it
And why would you want to do that?
 
Rotan72 said:
u can swallore some lemon to reduce fat. I heard some people does it
Oh my god! What is your esophagus's diameter!? I can swallow a lot of things but not some lemons!
 
Mk I don't think he ment whole. Lol.

I'm with Monique. Why would you want to do that?

~Kitty
 

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