Are there any other Macronutrients?

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Discussion Overview

The discussion centers around the concept of macronutrients, specifically questioning whether there are any additional macronutrients that contribute energy to the body beyond carbohydrates, proteins, and fats. It also explores the role of hydrochloric acid (HCl) in the digestion of these macronutrients.

Discussion Character

  • Exploratory
  • Technical explanation
  • Conceptual clarification

Main Points Raised

  • One participant questions if there are other macronutrients that provide energy aside from carbohydrates, proteins, and fats.
  • Another participant defines macronutrients as water (non-caloric), fats, carbohydrates, and proteins, noting their roles in homeostasis and tissue repair.
  • Caloric values for macronutrients are presented, with fats providing 9 kCal/g and carbohydrates and proteins providing 5 kCal/g each.
  • HCl is described as primarily hydrolyzing proteins and creating an acidic environment that aids enzyme activity and micronutrient absorption.
  • Fat digestion is said to depend on bile production, while carbohydrates are broken down into simple sugars with the help of enzymes and bacteria, with some absorption occurring in the mouth.
  • Lower stomach acid levels may necessitate dietary changes or supplementation, with calcium citrate mentioned as a preferred supplement for better absorption in higher pH conditions.
  • Another participant emphasizes that while fats, carbohydrates, and proteins are essential for energy and raw materials, vitamins and trace elements are also necessary but do not provide energy.

Areas of Agreement / Disagreement

Participants express varying views on the definition and role of macronutrients, with no consensus on the existence of additional energy-providing macronutrients. The discussion remains unresolved regarding the broader implications of HCl in digestion and nutrient absorption.

Contextual Notes

The discussion includes references to the effects of dietary changes on intestinal pH and the historical shifts in dietary sodium and potassium ratios, which may influence nutrient absorption but are not fully explored.

mktsgm
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I have a few questions on energy from foods. Do we have any other macronutrients that contribute energy to the body other than carbohydrates, proteins and fats in our body? What is the role of Hydrochloric acid (HCL) in our stomach? Is the HCL involved in all three above macronutrient digestion?
 
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Macronutrients are: Water (non-caloric), fats, carbohydrates, and proteins. All of these provide basic building 'materials' for all of the functions your body does for homeostasis, and daily tissue building/repair.

Approximate caloric values:
Water: Zero
Fats: 9 kCal/g
Carbohydrates: 5 kCal/g
Protein: 5 kCal/g

HCl is produced in the stomach to hydrolyze proteins (break them down into amino acids) primarily. And to provide a low pH environment favorable to enzyme activity there.
Acidity also facilitates absorption of some micronutrients in the intestine.

Fat digestion/absorption depends on bile production in the liver, carbohydrates break down into simple sugars in the presence of enzymes and bacteria. They can move though most of the mucosal membranes in the digestive tract. Acidity may play a small role. Ex: you can absorb glucose from fruit juice into your bloodstream in your mouth. Insulin dependent diabetics use fructose/glucose tablets to raise bad, low blood sugar levels by dissolving them in the mouth. This fast uptake of simple sugars is often discussed in the context of glycemic load and glycemic index.

Lower acid levels in the stomach (ex: antacid medicines or advanced age) may require supplementation or diet change. For example, Calcium citrate is sometimes preferred as a calcium supplement for older patients with problems like osteoporosis. It is better absorbed in a higher pH gut. I am oversimplifying here, as there may be a LOT of other issues involved, but the mian idea is that some citrate salts are better absorbed in people with low acid levels.

Diet is a factor on intestinal pH levels.

Here is a very interesting review of papers on the effects of changing:
pH, sodium, potassium, chloride, and carbonate levels
of humans diets over the past 200 years.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195546/

Note the complete reversal of potassium to sodium ratios.
Then: ~ 10 Potassium: 1 sodium
Now: ~ 1 Potassium: 3 sodium
The ~ character means 'approximately'
Chloride has also become far more prevalent.
 
Last edited:
Fats, carbohydrates and proteins provide all the energy and essential raw materials that our bodies require.
In addition to those we also need some vitamins and trace elements, but these are not energy sources.
They are needed in small quantities for some particular part of body chemistry.
For example we need iron for our red blood cells, vitamin C is necessary for a number of body repair and maintenance functions,
There is usually enough of these trace requirements present in food along with the three major categories
 
Thanks Jim and rootone.
 

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