Telomeres of neurons: Do they also become more short?

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The discussion centers on the behavior of telomeres in neurons, specifically questioning whether the Hayflick limit applies to them. It is established that neurons do not divide during the postnatal period, leading to the conclusion that terminally differentiated neuronal cells experience zero divisions. Additionally, it is noted that telomere length is not the sole determinant of cellular replication capacity.

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limarodessa
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Hello all! During mitosis the telomeres reduced. But neurons do not divide during postnatal period (neural stem cells are exclusion). So - does Hayflick limit exist for neurons?
Thanks
 
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Sure... the Hayflick limit is just the number of times a cell will divide. Most terminally differentiated neuronal cells would simply have zero divisions.

Also, note that telomere length is not the only factor determining the number of replications.
 

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