What is the molecular weight of Pluronic F-127?

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SUMMARY

The molecular weight of Pluronic F-127 is definitively established at approximately 12,000 Da. Conflicting information exists, with one source suggesting a calculation based on the nomenclature indicating a molecular weight of 3,600 Da. However, multiple reliable sources confirm the higher value of 12,000 Da. It is important to note that the molecular weight distribution of Pluronic polymers can be wide, which may complicate the selection of ultrafilters for applications.

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mrund3rd09
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I'm mainly concerned with Pluronic F-127.

I want to know it's molecular weight. On one source, it says that the molecular weight is roughly 12k Da. On the other hand, (and this is from wikipedia) it suggests that the 'F' stands for 'flake' or solid at room temperature, and the first 2 digits indicate the molecular weight of the polymer/300. So... F-127, first 2 digits, 12. 12*300 = 3600 Da, which is different from 12000 Da.

I have two conflicting sources, and I will be much more comfortable if I have a third source or even better fourth source that agrees with either one of these.

All I want is the molecular weight of F-127
 
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It is 12000. There are several sources on the net. It is probably an error in Wikipedia. The Mw distributionof these polymers tend to be very wide so if you are ploaning to use the Mw for the selection of ultrafilters, be advised that it may be more difficult than you expect to get a clean separation.
 

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