Changing a sum to an integral is applicable when the indexing value becomes continuous, allowing the sum to approximate an area under a curve through smaller elements. As the width of the boxes in the sum decreases, the approximation improves, leading to the use of integrals. However, if a term in the sum is significantly larger and cannot be treated as a small element, it cannot be integrated. The discussion also touches on Bose-Einstein condensation, questioning the separation of ground state particles from the integral due to their large number. This topic is suggested to be explored further in a dedicated thread focused on physics.