Which DNA Strand is the Template for RNA?

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SUMMARY

The template strand for RNA synthesis is determined by DNA-directed RNA polymerase, which relies on transcription factors for proper binding. These transcription factors facilitate the attachment of RNA polymerase to the specific DNA site where transcription initiates. Understanding this mechanism is crucial for comprehending gene expression and regulation.

PREREQUISITES
  • DNA-directed RNA polymerase
  • Transcription factors
  • Gene expression mechanisms
  • Basic molecular biology concepts
NEXT STEPS
  • Study the role of transcription factors in gene regulation
  • Learn about the process of transcription initiation
  • Explore the differences between introns and exons
  • Investigate the function of stop codons in protein synthesis
USEFUL FOR

Molecular biologists, geneticists, and students studying gene expression and transcription processes will benefit from this discussion.

clouded.perception
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How does RNA "know" which DNA strand is the template strand?
 
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Are you asking about introns and exons? Or the "stop" codon? Or something else?
 
clouded.perception said:
How does RNA "know" which DNA strand is the template strand?

It's the DNA-directed RNA polymerase that has to "know" which strand is the template, and that is determined by the binding of transcription factors that help the polymerase attach to the site where transcription will start.
 

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