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- TL;DR
- The Nobel Prize in Chemistry 2020 was awarded jointly to Emmanuelle Charpentier and Jennifer A. Doudna "for the development of a method for genome editing."
The discussion centers around the 2020 Nobel Prize in Chemistry, specifically regarding the recipients and the omission of certain researchers, particularly focusing on the contributions of Jennifer A. Doudna and Emmanuelle Charpentier in relation to CRISPR technology.
Participants express disagreement regarding the recognition of Siksnys's contributions, with some feeling he should have been included among the laureates, while others focus on the awarded researchers without addressing this point directly. The discussion remains unresolved regarding the implications of these omissions.
There are references to specific findings and contributions related to CRISPR technology, but the discussion does not clarify the full scope of each researcher’s work or the criteria for Nobel Prize selection.
crispr-researcher-wins-spotlight]From a 2018 article[/url] - about a prize awarded to him and the two (now) Nobel Prize winners.because his part in the discovery of CRISPR often has been overlooked
atyy said:No prize for Siksnys?
https://www.nobelprize.org/uploads/2020/10/advanced-chemistryprize2020.pdfSimilar findings were also published in another report using the related CRISPR-Cas system in Streptococcus thermophilus. As in Charpentier and Doudna’s work, this report also demonstrated that Cas9 cleaves within the protospacer, that cleavage specificity is directed by the crRNA sequence, and that the two nuclease domains within Cas9, each cleave one strand. However, the researchers did not notice the crucial importance of tracrRNA for sequence-specific cleavage of target DNA [29].