...is a polynomial inequality in 26 variables, and the set of prime numbers is identical to the set of positive values taken on by this polynomial inequality as the variables a, b, …, z range over the nonnegative integers.
A general theorem of Matiyasevich says that if a set is defined by a system of Diophantine equations, it can also be defined by a system of Diophantine equations in only 9 variables. Hence, there is a prime-generating polynomial as above with only 10 variables. However, its degree is large (in the order of 10^45). On the other hand, there also exists such a set of equations of degree only 4, but in 58 variables (Jones 1982).