What Does the Chromosome Diagnosis Notation t(4;11)(p16;p15) Mean?

Thread starter Bio-student
Start date Apr 17, 2011
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The discussion centers on the chromosomal translocation t(4;11)(p16;p15), indicating a genetic rearrangement between chromosomes 4 and 11. The notation (p16;p15) specifies the locations of the translocation on the short arms (p arms) of the chromosomes, with 16 and 15 referring to specific bands within those arms. For further clarification on genetic nomenclature, a link to a Wikipedia page on locus nomenclature is provided, which can help in understanding the significance of these band locations in chromosome diagnosis.

Apr 17, 2011

Bio-student

t(4;11)(p16;p15)

Hi, what would the above mean in terms of chromosome diagnosis? I understand a translocation has occurred between chromosomes 4 and 11, but not what (p16;p15) means.

Thanks.

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Apr 17, 2011

bobze

Science Advisor

Gold Member

The 16 and 15 bands on the respective p arm.

Apr 18, 2011

mishrashubham

Take a look at this.
http://en.wikipedia.org/wiki/Locus_(genetics)#Nomenclature

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