That is much of what happens in so called ufology: Can the alleged event be explained in conventional terms? Debunkers posit their explanations, and if appropriate, ufologists counter with scientific arguments that appear to contradict those explanations. Sometimes it is a simple matter of the explanation failing to answer the reported facts, and no science is required; only a simple reading of the report.
Probably the single biggest factor that motivated my own interest in the subject was that some of the explanations offered for the most striking reports were obviously nonsense. Maybe the event never happened, or maybe the witnesses are exaggerating, delusional, or even lying, but in no way did some of these explanation account for the reported facts.
I can still remember my first exposure in I think Sky and Telescope magazine, that really got my attention. It was the JAL 1628 event. This goes back, but IIRC, it was Phil Klass who suggested that what was reported by a commercial pilot - a craft the size of an aircraft carrier - was in fact, Venus, which was unusually bright that night. I knew almost nothing about the subject, but anyone could see that this explanation for the report made no sense.
http://www.ufoevidence.org/topics/JALalaska.htm
Dr. Peter A. Sturrock, Professor of Space Science and Astrophysics, from Stanford, has addressed the summary report of the Condon committee, which is argued to ignore the findings of its own investigation and investigators. This is all linked in the Napster. You be the judge.
Dr. J. Allen Hynek, a Professor of Astronomy from Northwestern, who was the first official government debunker - the chief scientist for project Bluebook - and the originator of the swamp gas explanation for some UFO reports, later debunked himself and became the father of modern ufology.
Dr. Bruce Maccabee, who works as an optical physicist for the Navy Dept [who has posted here a few times], is known for his role as a debunker, and as a debunker debunker.