- #1
Juche
- 36
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Assume you have a med with a 72 hour half life, but that is dosed daily. How much elimination occurs each day of the drug, and what is the steady state dose compared to the daily dose?
Is it just a linear decrease, so you take 50/72= 0.667, and multiply 0.667x24= 16 which means everyday 16% of the drug in your system is destroyed, and you have 100/16=6 so 6 times as much as the daily dose in your system at any given time (ie if you take 10mg a day you have a steady state level of 60mg in your body)?
If drug half life is exponential I don't know how to solve it.
Is it just a linear decrease, so you take 50/72= 0.667, and multiply 0.667x24= 16 which means everyday 16% of the drug in your system is destroyed, and you have 100/16=6 so 6 times as much as the daily dose in your system at any given time (ie if you take 10mg a day you have a steady state level of 60mg in your body)?
If drug half life is exponential I don't know how to solve it.