- #1
chops369
- 56
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Can someone please help me understand the difference between syn and anti elimination in terms of what they favor? My [extremely] limited understanding leads me to believe that syn elimination favors E2 since it mimics frontside attack, which will not work for Sn2 since there is no net-bonding when the nucleophile attacks the empty sigma antibonding orbital from this angle. I would also venture that anti elimination favors Sn2 since it mimics backside attack. Is this the only difference between the two arrangements? Please correct if I'm wrong.