Telomeres of neurons: Do they also become more short?

limarodessa

Hello all! During mitosis the telomeres reduced. But neurons do not divide during postnatal period (neural stem cells are exclusion). So - does Hayflick limit exist for neurons?
Thanks

zhermes

Sure... the Hayflick limit is just the number of times a cell will divide. Most terminally differentiated neuronal cells would simply have zero divisions.

Also, note that telomere length is not the only factor determining the number of replications.

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limarodessa	Telomeres of neurons: Do they also become more short? Tweet Hello all! During mitosis the telomeres reduced. But neurons do not divide during postnatal period (neural stem cells are exclusion). So - does Hayflick limit exist for neurons? Thanks

zhermes	Sure... the Hayflick limit is just the number of times a cell will divide. Most terminally differentiated neuronal cells would simply have zero divisions. Also, note that telomere length is not the only factor determining the number of replications.