How does light affect our internal clock and influence wakefulness?

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Photons play a crucial role in regulating wakefulness by activating specific hormones in the body. The discussion centers on whether these photons need to directly hit the eyes or if they can affect the body in other ways. It is noted that light can penetrate closed eyelids, which raises questions about the importance of functional eyes versus the presence of eyes for circadian regulation. Research indicates that blind individuals may experience free-running circadian rhythms, suggesting that the mechanism of light perception is complex. The conversation references various scientific studies and literature, including the role of melanopsin in light detection and its implications for treating circadian rhythm disorders. The effectiveness of devices designed to simulate light exposure in areas like the knee pit is also questioned, highlighting the need for further investigation into how light influences wakefulness and circadian rhythms.
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Photons hit our eyes or bodies which activate a certain hormone which causes us to wake up. Does anyone know if the photons have to hit your eye or your body?
 
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atyy said:
Not that I am aware of. There was a time that anti-jetlag devices were sold that were placed in the knee pit, but I'd be interested to know whether they really work. A clue comes from people who are blind, the publications I have seen report that they have free-running circadian periods.
 
About blind people, I mean photons hitting your closed eyelids
 
robertjford80 said:
About blind people, I mean photons hitting your closed eyelids

What do you mean? Light still penetrates the eye when the eyelids are closed.
 
Blind people have eyes, they just don't work, unless they've been gouged out which is very rare. So what point are you trying to make then with blind people?
 
Think for one second. Your question was: "Does anyone know if the photons have to hit your eye or your body?".

If blind people have problems waking up, do you think their body is important or their eyes? Also, do you think it is having eyes that is important or having visually functional eyes?
 
Here's what I originally read, I decided to track it down. This comes from the Harvard Medical Guide to Sleep

light, focused on the back of the eye, can be used to reset the internal clock and treat circadian rhythm disorders such as jet lag

Somehow the first part of the sentence got cut off, so I'll have to look at the original book to see what got cut off but that's at home.
 
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