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Can we calculate the exact number of receptors on E.Coli membrane? 
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#1
Mar2714, 02:00 PM

P: 138

I have heard that nobody really knows how many receptors are placed on E.Coli cell membrane. Of course we know the general types of the proteins incorporated in membrane (Carrier proteins, Na+/K+ATPase, various transporters, Ion channels) but I need to know the exact number of types and exact total number of receptors on E.Coli membrane. Actually there is a article in Wikipedia but it does not give us this number.
So, what can you tell me about this? Has anybody counted them? If there is a better webforum for microbiology then tell me and I will post this question there 


#2
Mar2714, 10:12 PM

Other Sci
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P: 1,403

The following paper has measured the copy number of nearly every protein in E. coli:
Taniguchi et al. 2010 Quantifying E. coli Proteome and Transcriptome with SingleMolecule Sensitivity in Single Cells. Science 329: 533. doi:10.1126/science.1188308. 


#3
Mar2814, 11:55 AM

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#4
Mar3014, 12:16 PM

P: 138

Can we calculate the exact number of receptors on E.Coli membrane?
Please tell me why we cannot simply count the number of receptors? Cannot the Scanning probe microscope or the Scanning electron microscope scan the plasmatic membrane and see any roughness on it? Such roughness would be the receptors.
Ygggdrasil Did I miss something there? Andy Resnick 


#5
Mar3014, 12:39 PM

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P: 1,403

The bionumbers database, says the there are ~200000 proteins in the inner membrane of E. coli and ~300000 proteins in the outer membrane: http://bionumbers.hms.harvard.edu//b...d=100083&ver=3 


#6
Mar3114, 01:47 PM

P: 138

Ygggdrasil



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