Register to reply 
Can we calculate the exact number of receptors on E.Coli membrane? 
Share this thread: 
#1
Mar2714, 02:00 PM

P: 134

I have heard that nobody really knows how many receptors are placed on E.Coli cell membrane. Of course we know the general types of the proteins incorporated in membrane (Carrier proteins, Na+/K+ATPase, various transporters, Ion channels) but I need to know the exact number of types and exact total number of receptors on E.Coli membrane. Actually there is a article in Wikipedia but it does not give us this number.
So, what can you tell me about this? Has anybody counted them? If there is a better webforum for microbiology then tell me and I will post this question there 


#2
Mar2714, 10:12 PM

Other Sci
Sci Advisor
P: 1,378

The following paper has measured the copy number of nearly every protein in E. coli:
Taniguchi et al. 2010 Quantifying E. coli Proteome and Transcriptome with SingleMolecule Sensitivity in Single Cells. Science 329: 533. doi:10.1126/science.1188308. 


#3
Mar2814, 11:55 AM

Sci Advisor
P: 5,510




#4
Mar3014, 12:16 PM

P: 134

Can we calculate the exact number of receptors on E.Coli membrane?
Please tell me why we cannot simply count the number of receptors? Cannot the Scanning probe microscope or the Scanning electron microscope scan the plasmatic membrane and see any roughness on it? Such roughness would be the receptors.
Ygggdrasil Did I miss something there? Andy Resnick 


#5
Mar3014, 12:39 PM

Other Sci
Sci Advisor
P: 1,378

The bionumbers database, says the there are ~200000 proteins in the inner membrane of E. coli and ~300000 proteins in the outer membrane: http://bionumbers.hms.harvard.edu//b...d=100083&ver=3 


#6
Mar3114, 01:47 PM

P: 134

Ygggdrasil



Register to reply 
Related Discussions  
Exact number of possible chess games  General Math  18  
Calculate odds ratio and fisher's exact text  Set Theory, Logic, Probability, Statistics  2  
Amount of receptors required for depolarisation of post synaptic membrane.  Biology, Chemistry & Other Homework  0  
Exact number of zeros for any given continuous function  Calculus  3  
How to calculate the exact wavefunction of two electrons in a 1d infinite well?  Quantum Physics  7 