The probability of a child inheriting an autosomal recessive disorder from their parents is 25%, or 1 in 4. This means that there is a 25% chance that the child will inherit two copies of the mutated gene, one from each parent, and will develop the disorder.
Yes, it is possible for two carriers of an autosomal recessive disorder to have a child without the disorder. This would occur if the child inherits one copy of the mutated gene from one parent, but a normal copy of the gene from the other parent. In this case, the child would be a carrier like their parents, but would not develop the disorder.
Autosomal recessive disorders are inherited when a child receives two copies of a mutated gene, one from each parent. Both parents are typically carriers of the mutated gene, meaning they have one normal copy of the gene and one mutated copy. If a child inherits two normal copies of the gene, they will not develop the disorder.
Yes, some autosomal recessive disorders are more common in certain populations or ethnicities due to genetic drift and founder effects. For example, cystic fibrosis is more common in individuals of European descent, while sickle cell anemia is more prevalent in individuals of African descent.
Yes, it is possible for an autosomal recessive disorder to skip generations in a family. This occurs when a child inherits one copy of the mutated gene from a carrier parent, but the other parent does not carry the mutated gene. In this case, the disorder may not manifest in the child, but may reappear in future generations if two carriers have children together.