Where Can I Find 2D Structures of Molecules Like Melanin?

Click For Summary
SUMMARY

This discussion centers on finding 2D structures of melanin, a complex pigment that is not easily defined due to its macromolecular nature. Participants highlight that traditional databases like Swissprot and Entrez are inadequate for this purpose. Richard E. Barrans Jr., Ph.D., emphasizes that melanin consists of various polymers derived from indole-type chemical units, primarily formed from tyrosine and dopa. Users recommend resources such as ChemFinder and ACD Labs for molecular modeling and visualization.

PREREQUISITES
  • Understanding of macromolecular structures and their properties
  • Familiarity with chemical databases like Swissprot and Entrez
  • Knowledge of melanin's biochemical precursors, specifically tyrosine and dopa
  • Basic skills in molecular modeling software
NEXT STEPS
  • Explore ACD Labs for molecular structure visualization tools
  • Research the optical properties of melanin and its monomers
  • Investigate additional databases for chemical structures, such as ChemSpider
  • Learn about the synthesis pathways of melanin from various substrates
USEFUL FOR

Chemists, biochemists, and researchers interested in pigment structures, molecular modeling, and the biochemical properties of melanin.

Monique
Staff Emeritus
Science Advisor
Gold Member
Messages
4,215
Reaction score
61
Which are good databases to find 2D structures of molecules like the following:
http://www.accelrys.com/cases/images/melanin2.jpg
It is supposed to be a form of melanin, but I need a better one :)

Swissprot won't work, since it is not a protein.. couldn't find anything in Entrez either :(
 
Last edited by a moderator:
Biology news on Phys.org
WHOA! Is THIS melanin??

http://www.rastafarian.net/melanin2.jpg

no wonder it is good at absorbing energies too bad the two structures don't match
 
*grmbl* the following doesn't help..

Melanin Model

name Alexis
status other
age 30s

Question - Where can I find a molecular model (chemical structure
and drawing) of melanin pigment?
------------------------------------------------
I don't think you'll have much luck. The fact that melanin is a "pigment"
should tip you off. Pigments are generally ill-defined, insoluble
macromolecules, and melanin is (more correctly, melanins are) no exception.
From the Merck Index: "Structures are macromolecules, probably mixtures of
polymers, produced by enzyme systems from various precursors in the form of
granules and may be bound to protein material. ... The chemical units which
predominate in these melanins are of the indole type, formed from tyrosine
and dopa precursors."

Richard E. Barrans Jr., Ph.D.
Assistant Director
PG Research Foundation, Darien, Illinois
===================================
I need to have the structure though!
 
Looks like that was all I could find as well. Maybe you could post an easier question?

http://www.accelrys.com/cases/images/melanin3.jpg
http://www.accelrys.com/cases/images/melanin2.jpg
 
Last edited by a moderator:
Originally posted by rockind78
Maybe you could post an easier question?
well..

But what are some databases where structures are deposited, or databases which list properties of molecules.. I already mentioned Swissprot/Expasy and Entrez.. I used to know lots others, but haven't used any of them in yearsss :)
 
Oh well, I guess I can just list the compounds which can be used as substrates for melanin production. Ofcourse it is pretty evident there is no one form of melanin, since every person's skin color is different.. the melanin of asians will be very different from africans or from skandinavians..

I am actually looking for a melanin from a fungus, it also protects them from UV damage, pretty cool :) that is why spoiled food gets such pretty nasty colorations :P
 
The idea behind all this is that the ringstructures of melanin produce the color and enable it to absorb energies
 
Optical Absorption of Melanin

This has the structure of the melanin monomers available, as well as some information on synthesis and optical properties.
 
How about making your on.

download this free program, sketch in the formula and the you can view in 2D or 3D

http://acdlabs.com/download/

Nautica
 
  • #10

Similar threads

  • · Replies 1 ·
Replies
1
Views
2K
  • · Replies 4 ·
Replies
4
Views
3K
Replies
7
Views
5K
Replies
11
Views
2K
Replies
1
Views
2K
  • · Replies 6 ·
Replies
6
Views
3K
Replies
2
Views
3K
Replies
4
Views
5K
  • · Replies 1 ·
Replies
1
Views
5K
Replies
1
Views
2K