SUMMARY
This discussion centers on finding 2D structures of melanin, a complex pigment that is not easily defined due to its macromolecular nature. Participants highlight that traditional databases like Swissprot and Entrez are inadequate for this purpose. Richard E. Barrans Jr., Ph.D., emphasizes that melanin consists of various polymers derived from indole-type chemical units, primarily formed from tyrosine and dopa. Users recommend resources such as ChemFinder and ACD Labs for molecular modeling and visualization.
PREREQUISITES
- Understanding of macromolecular structures and their properties
- Familiarity with chemical databases like Swissprot and Entrez
- Knowledge of melanin's biochemical precursors, specifically tyrosine and dopa
- Basic skills in molecular modeling software
NEXT STEPS
- Explore ACD Labs for molecular structure visualization tools
- Research the optical properties of melanin and its monomers
- Investigate additional databases for chemical structures, such as ChemSpider
- Learn about the synthesis pathways of melanin from various substrates
USEFUL FOR
Chemists, biochemists, and researchers interested in pigment structures, molecular modeling, and the biochemical properties of melanin.