Analytical Chemistry involving buffer

In summary, a buffer solution is a solution that resists changes in pH, made up of a weak acid or base and its conjugate salt. They are important in analytical chemistry for maintaining a constant pH and allowing for accurate measurements. Buffer solutions can be prepared by mixing a weak acid or base with its conjugate salt in a specific ratio. They are only effective within a specific pH range, determined by the pKa of the weak acid or base. The appropriate buffer for a specific experiment should be chosen based on the desired pH range, pKa, and compatibility with other substances.
  • #1
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Homework Statement



What volume of 0.200M HCl must be added to 250.0ml of 0.300M sodium mandelate to produce a buffer solution with a pH of 3.37?


Homework Equations


The Attempt at a Solution



For 2 and 3, can I use the equation pH = pKa + log [A-/HA]? but for HCl isn't that 100% disassociation? How can we use that if the Ka is not a given value for HCl?

Thanks.
 
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  • #2
You are correct... Think of the HCl being used only to protonate a portion of the sodium mandelate.
 
  • #3
And assume this protonation is stoichiometric.
 

1. What is a buffer solution?

A buffer solution is a solution that resists changes in pH when small amounts of acid or base are added. It is made up of a weak acid or base and its conjugate salt, which work together to maintain a stable pH.

2. Why are buffer solutions important in analytical chemistry?

Buffer solutions are important in analytical chemistry because they help to maintain a constant pH, which is crucial for many chemical reactions and experiments. They also allow for accurate and precise measurements of pH, which is essential for determining the concentration of a substance in a solution.

3. How do you prepare a buffer solution?

A buffer solution can be prepared by mixing a weak acid or base with its conjugate salt in a specific ratio. The desired pH of the buffer can be achieved by adjusting the concentrations of the acid and conjugate base. It is important to use high purity chemicals and accurate measurements to prepare a reliable buffer solution.

4. Can a buffer solution be used for any pH?

No, a buffer solution is only effective in maintaining a stable pH within a specific range. This range is determined by the pKa of the weak acid or base used in the buffer. A buffer solution with a pKa close to the desired pH will be most effective in maintaining that pH.

5. How do you choose the appropriate buffer for a specific experiment?

The appropriate buffer for a specific experiment should be chosen based on the desired pH range and the pKa of the weak acid or base. Additionally, the compatibility of the buffer with the substances and conditions present in the experiment should also be considered. It is important to select a buffer that will not react with the substances being analyzed or interfere with the results.

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