Are ions always aqueous inside the cell? (simple question)

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    Aqueous Cell Ions
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Discussion Overview

The discussion centers on the nature of hydrogen ions within cells, specifically whether they exist in an aqueous state and how they are transported across cell membranes. It explores concepts related to diffusion, osmosis, and the mechanisms of ion transport in biological systems.

Discussion Character

  • Exploratory
  • Technical explanation
  • Conceptual clarification

Main Points Raised

  • One participant questions whether hydrogen ions inside the cell are always dissolved in water, suggesting that ions cannot exist without being dissolved and inquiring about their reactivity.
  • Another participant acknowledges the complexity of the relationship between osmosis and ion diffusion.
  • It is proposed that hydrogen ions can move into the cell either while dissolved in water or through membrane pumps, where they are not necessarily dissolved.
  • A third mechanism is introduced, suggesting that protons can form complexes with water molecules and move efficiently through hydrogen bonding, allowing them to be transported without traditional pumps or proteins.

Areas of Agreement / Disagreement

Participants present multiple competing views on the mechanisms of hydrogen ion transport and whether they are always aqueous, indicating that the discussion remains unresolved.

Contextual Notes

There are limitations regarding the assumptions about the state of ions and the definitions of transport mechanisms, which are not fully resolved in the discussion.

sameeralord
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Hello guys,

So there are hydrogen ions inside the cell which is pumped out in cellular respiration. Now my question is when they say hydrogen ions are inside the cell are these actually dissolved in water, ions can not exist without being dissolved right, why is that they are so reactive otherwise. Also in diffusion when they say hydrogen ions are taken in by the cell, does water come with it because they are dissolved. So does osmosis and ion diffusion occur together. Thanks :smile:
 
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So does osmosis and ion diffusion occur together.
A good but complex question for sure.
 
There are at least a couple mechanisms by which hydrogen ions could move into the cell. They can be transported while dissolved in water, yes, but lone protons can also be transported through membrane pumps. Here they aren't dissolved in water but are rather transferred between transmembrane proteins. This is described in detail in cell biology texts that focus on the plasma membrane.
 
There is a third but accepted mechanism : No pump, no protein and it works fine.
http://www.amolf.nl/news/news-archive/detailpage/back_to/news-archive/article/water-lends-protons-a-helping-hand//chash/ddde2cfa66/
http://www.spectroscopynow.com/coi/cda/detail.cda?id=10474&type=Feature&chId=2&page=1
Protons do not move freely in water, but form complexes with water molecules through hydrogen bonds, which allow protons to hop through water very efficiently. "One could use the picture of improving a dike with sandbags", explains Nibbering. A chain of people can transport the sandbags to the dike more efficiently and faster than each person working individually. Thus, protons hope from water molecule to molecule, just as sandbags hop from person to person.
 
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