Which Cell Types Have High Density of Cytoplasmic Intermediate Filaments?

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SUMMARY

The discussion centers on identifying cell types with a high density of cytoplasmic intermediate filaments. It concludes that human skin epithelial cells and nerve cells in the spinal cord of a mouse are the most likely candidates due to their structural and functional requirements. Cytoplasmic intermediate filaments serve as tension-bearing elements, crucial for maintaining cell shape and anchoring organelles. The discussion references a chapter from the National Center for Biotechnology Information (NCBI) detailing the role of intermediate filaments in cellular integrity.

PREREQUISITES
  • Understanding of cytoplasmic intermediate filaments
  • Knowledge of cell structure and function
  • Familiarity with human anatomy, specifically epithelial and nerve cells
  • Basic concepts of cellular organelles and their roles
NEXT STEPS
  • Research the role of cytoplasmic intermediate filaments in cellular mechanics
  • Explore the structural differences between epithelial and nerve cells
  • Study the function of desmosomes in cell adhesion
  • Review the chapter on intermediate filaments from the NCBI resource
USEFUL FOR

Cell biologists, histologists, and students studying human anatomy or cellular biology will benefit from this discussion, particularly those interested in the structural roles of intermediate filaments in various cell types.

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Which of the following types of cells would you expect to contain a high density of cytoplasmic intermediate filaments?

A) Free living amoeba (the answer is no, but why? Is it because the amoeba has to move)

B) Human skin epithelial cell

C) smooth cell in the digestive tract of a vertebrate

D) Nerve cell in the spinal cord of a mouse

E) Human sperm cell

F) Plant cell

Any help would be appreciated :smile:
 
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First, the cytoplasmic intermediate filaments has only been isolated in on type of cell and this would help eliminate two choice.

Second, ask yourself what is the role of the cytoplasmic intermediate filaments.

Based on their function what cell type needs this function the most. That should eliminate two more choice.

The answer is bit more difficult to find. You may find what you want in the chapter.
http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=mboc4.section.2957
 
INtermediate filaments function as tension-bearing elements to help maintain cell shape and rigidity, and serve to anchor in place several organelles, including the nucleus and desmosomes

Ok if this is true then wouldn't a nerve cell in the spinal cord of a mouse need the filaments to maintain the structure and rigidity of the cell.

Also human skin epithelial cell would need the filaments to maintain structure of human skin
 

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