Connecting a metal sphere to a battery while grounding the other end will indeed charge the sphere. The charge on the sphere can be calculated using the formula Q=VR, where V is the voltage and R is the resistance. Despite the simplicity and lower cost of this method, Van de Graaff generators are preferred in laboratories due to their ability to produce significantly higher voltages, often exceeding 50,000 volts. While it is theoretically possible to increase battery voltage to match that of a Van de Graaff generator using converters, practical implementations for achieving such high voltages with batteries are challenging. Ultimately, the choice of charging method depends on the specific voltage requirements and practical considerations.