What is the Capacity Factor of Glycolysis in Cells?

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SUMMARY

The capacity factor of glycolysis in cells refers to the maximum rate of ATP production under constant extracellular glucose concentrations. This rate varies by cell type and is influenced by both passive and active glucose uptake mechanisms. The discussion highlights the importance of understanding these rates in relation to the average energy production needs of cells. For detailed data, the BioNumbers database and its associated online textbook are recommended resources.

PREREQUISITES
  • Cellular metabolism fundamentals
  • Understanding of ATP production mechanisms
  • Knowledge of glucose transport processes
  • Familiarity with the cell cycle and its phases
NEXT STEPS
  • Research glycolysis rates in different cell types
  • Explore the BioNumbers database for quantitative data
  • Study the mechanisms of glucose uptake in cells
  • Investigate the relationship between glycolysis and the cell cycle
USEFUL FOR

Students and researchers in cell biology, biochemists studying metabolic pathways, and anyone interested in the energy dynamics of cellular processes.

Boomer Dave
Hello. I'm in the process of teaching myself cell bio and I'm curious to find a good source with actual rates of glycolysis in cells. In a nutshell, I'm wondering what the maximum rate of ATP production within the cell is (assuming a normal yet constant extracellular concentration of glucose) and how this compares to the average needs of the cell (normal rate of energy production/use). This would be like asking for the capacity factor of a power plant. I realize this probably varies by cell type and there appears to be both passive and active glucose uptake (not that this is necessarily the rate-limiting process), but any explanation or directions to a solid source would be greatly appreciated. Also, I'm trying to get a good idea of the the order of magnitude and how it changes during the cell cycle.
 
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