Cause of gray hair and actual ageing

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Discussion Overview

The discussion revolves around the causes of gray hair and the biological processes associated with aging. Participants explore the relationship between chemical changes in the body, particularly the role of melanin and melanocytes, in the graying of hair.

Discussion Character

  • Exploratory, Technical explanation, Conceptual clarification, Debate/contested

Main Points Raised

  • One participant mentions that an increase in catalase may help reduce gray hair by feeding peroxide, while also noting that heme-Fe increases with age, leading to confusion about these processes.
  • Another participant asserts that as people age, there is a decrease in the chemical responsible for keeping hair dark, suggesting a need to identify this chemical.
  • A later reply identifies melanin as the chemical responsible for hair color, explaining that melanocytes produce eumelanin and pheomelanin, which contribute to hair pigmentation.
  • Participants discuss the process by which melanocytes become less active with age, leading to less pigment being deposited in hair, resulting in a graying appearance.
  • There is a question about whether all cells die off, to which another participant clarifies that only the colored melanocytes die, leading to gray hair.
  • One participant emphasizes that the loss of melanocytes is not necessarily age-related.

Areas of Agreement / Disagreement

Participants express varying views on the relationship between aging and the graying of hair, with some suggesting a direct connection to age while others argue that the process may not be strictly age-related. The discussion remains unresolved regarding the exact mechanisms and factors involved.

Contextual Notes

There are limitations in the discussion regarding the assumptions about the relationship between catalase, heme-Fe, and the aging process, as well as the specific roles of melanocytes and melanin in hair pigmentation.

Medicol
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I have learned that a catalase increase may help feed peroxide and reduce gray hair but on the other hand human ageing states that its heme-Fe increases automatically overtime. These two "facts" really confuses me. Could you help me explain this ? Thank you.
 
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As we age their is less of the chemical that keeps the hair dark!

We need to find out this chemical!
 
Last edited by a moderator:
oracle21 said:
As we age their is less of the chemical that keeps the hair dark!

We need to find out this chemical!
The chemical is melanin.

What causes your hair's color to change? That has to do with the process controlling the production of the pigment called melanin, the same pigment that tans your skin in response to sunlight.

Every hair follicle contains pigment cells called melanocytes. The melanocytes produce eumelanin, which is black or dark brown, and pheomelanin, which is reddish-yellow, and pass the melanin to the cells which produce keratin, the chief protein in hair. When the keratin-producing cells (keratinocytes) die, they retain the coloring from the melanin. When you first start to go gray, the melanocytes are still present, but they become less active. Less pigment is deposited into the hair so it appears lighter. As graying progresses, the melanocytes die off until there aren't any cells left to produce the color.

http://chemistry.about.com/od/howthingsworkfaqs/f/why-does-hair-turn-gray.htm
 
Do all the cells die off?
 
Just the colored ones.
 
Think You!
 
Tell me about the colored one's?
 
Melanocytes is the short answer. The produce the pigments that color hair. When they die out you get grey hair. It is not necessarily age related.
 

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