Where are you haveing trouble?
You already had
[tex]J=\int_{u_1}^{u_2} (ye^{u^4}du+3u^3e^{u^4}du+3u^2du)[/tex]
and vela pointed out that, since [itex]y= u^3[/itex], that is the same as
[tex]J=\int_{u_1}^{u_2} (u^3e^{u^4}du+3u^3e^{u^4}du+3u^2du)[/tex]
so it is really just
[tex]J=\int_{u_1}^{u_2} (4u^3e^{u^4}du+3u^2du)[/tex]
You are told that x runs from 1 to 6. When x= 1 what is u? When x= 6, what is u?
If you still can't do it, please show your work so we can see exactly where you have a problem.