COVID COVID-19 Coronavirus Containment Efforts

AI Thread Summary
Containment efforts for the COVID-19 Coronavirus are facing significant challenges, with experts suggesting that it may no longer be feasible to prevent its global spread. The virus has a mortality rate of approximately 2-3%, which could lead to a substantial increase in deaths if it becomes as widespread as the flu. Current data indicates around 6,000 cases, with low mortality rates in areas with good healthcare. Vaccine development is underway, but it is unlikely to be ready in time for the current outbreak, highlighting the urgency of the situation. As the outbreak evolves, the healthcare system may face considerable strain, underscoring the need for continued monitoring and response efforts.
  • #51
What does Taiwan have to say about this?
Territory of China?
 

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  • #52
chemisttree said:
Patients 3 and 4 had no contact with the (now symptomatic) index patient. I believe patients #3 and #4 contracted it from patient #1 before he had symptoms.
StatGuy2000 said:
According to your chart above, it looks like Patient 4 had contact with Patient 1 on the very verge that Patient 1 was displaying symptoms, and thus more likely to be able to infect others (other coronaviruses have been show to be transmissible through droplets released during breathing).

I'm also curious as to how investigators were able to confirm which dates Patients 3 and 4 had contact with Patient 1. It's difficult to be precise about these timelines, so I'm not sure that it really tells us just how transmissible the Coronavirus is.

Just to clarify, the possibility still exists that asymptomatic individuals can spread the disease, we just don't have solid evidence of whether or not this is true. There have been anecdotal reports from doctors in China that this is the case (discussed in the Science news piece I posted earlier), but we await further evidence. Hopefully, the doctors in Germany who published the NEMJ piece can provide an updated paper to clarify how patients 3 and 4 were infected.
 
  • #53
Countdown to “SARS Level Lethality” is about 4 days now.

https://ncov.r6.no/
 
  • #54
kadiot said:
What does Taiwan have to say about this?
Territory of China?
I’ve seen blog posts asserting that China essentially owns the WHO. China objected to Taiwan’s inclusion in the WHO and so Taiwan isn’t a member. This is just another datapoint supporting that assertion.

What does Taiwan have to say? Taiwan is “outraged.”

https://www.worldtribune.com/taiwan...part-of-china-on-who-coronavirus-declaration/
 
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  • #55
I just finished watching a virologist talk about the latest with this virus. He said human to human transmission has been confirmed - its droplet spread. The death rate is about 5%.

But keep calm - the silver bullet is coming. We now have the technology to create vaccines very quickly - evidently the University of Queensland near were I live (as mentioned previously it swung into action immediately and is making progress at an amazing rate) has just completed the first one, or it soon will be completed. The two enablers are the synthesized virus created by the University of Melbourne and the 'molecular clamp' technology (whatever that is) invented and patented by UQ scientists.


I had no idea our local university was so advanced. Then its to trials and mass production. The thinking is April when it can be used by humans and ready for mass inoculation a bit after that - certainly all in a maximum of a 6 months time frame.

The virologists concern was we do not know how fast it is mutating. It's very similar to both a virus that causes the common cold and the even deadlier SARS virus. If it goes in the cold direction it may just peter out - if it goes in the SARS direction then its all stops out on the vaccine.

Finger's crossed - but it seems we have the technology.

Added later: Watching TV makes me think people are really starting to worry. If you live in a modern country like the US, UK ,or Australia - don't. With modern care I think the death rate will be much lower than 5% - maybe about the same as the flu. I am a hypochondriac with a comprised immune system from two drugs - Methotrexate and a Biologic and even I am not worried despite being the exact person that would be in trouble if they got it. What they found with the the SARS virus was even simply ensuring you wash your hands frequently and certainly every time you use the bathroom made a big difference.


Thanks
Bill
 
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  • #56
chemisttree said:
I’ve seen blog posts asserting that China essentially owns the WHO. China objected to Taiwan’s inclusion in the WHO and so Taiwan isn’t a member. This is just another datapoint supporting that assertion.

What does Taiwan have to say? Taiwan is “outraged.”

https://www.worldtribune.com/taiwan...part-of-china-on-who-coronavirus-declaration/
With cases that are confirmed I just don't know the reason why Taiwan was removed.
 
  • #57
bhobba said:
I just finished watching a virologist talk about the latest with this virus. He said human to human transmission has been confirmed - its droplet spread. The death rate is about 5%.

But keep calm - the silver bullet is coming. We now have the technology to create vaccines very quickly - evidently the University of Queensland near were I live (as mentioned previously it swung into action immediately and is making progress at an amazing rate) has just completed the first one, or it soon will be completed. The two enablers are the synthesized virus created by the University of Melbourne and the 'molecular clamp' technology (whatever that is) invented and patented by UQ scientists.


I had no idea our local university was so advanced. Then its to trials and mass production. The thinking is April when it can be used by humans and ready for mass inoculation a bit after that - certainly all in a maximum of a 6 months time frame.

The virologists concern was we do not know how fast it is mutating. It's very similar to both a virus that causes the common cold and the even deadlier SARS virus. If it goes in the cold direction it may just peter out - if it goes in the SARS direction then its all stops out on the vaccine.

Finger's crossed - but it seems we have the technology.

Great news! Thanks.

Here's another one:

Scientists in Singapore have successfully cultured the Coronavirus from an infected patient’s clinical sample. This will help in developing new diagnostic methods, monitoring potential mutation and testing for potential vaccine and drugs. The team from Duke-NUS Medical School, Singapore General Hospital, National Centre for Infectious Diseases and MOH are the third country in the world outside China to do so. Read how scientists are racing against time to learn more about the 2019-nCoV.

https://www.moh.gov.sg/news-highlig...coronavirus-(the-sunday-times-2-feb-2020-pb6)

bhobba said:
Added later: Watching TV makes me think people are really starting to worry. If you live in a modern country like the US, UK ,or Australia - don't. With modern care I think the death rate will be much lower than 5% - maybe about the same as the flu.
How about Singapore? Is she considered a modern country?
 
  • #58
Ygggdrasil said:
Just to clarify, the possibility still exists that asymptomatic individuals can spread the disease, we just don't have solid evidence of whether or not this is true. There have been anecdotal reports from doctors in China that this is the case (discussed in the Science news piece I posted earlier), but we await further evidence. Hopefully, the doctors in Germany who published the NEMJ piece can provide an updated paper to clarify how patients 3 and 4 were infected.
The first confirmed case in the Philippines was detected using the DOH/WHO protocols in place and is asymptomatic. No definitive evidence of infectiousness in asymptomatic patients yet, although I've hrard it is possible. She had a mild cough.
 
  • #59
kadiot said:
How about Singapore? Is she considered a modern country?

Of course - its like asking is Japan a modern country :DD:DD:DD:DD:DD:DD:DD:DD:DD. I was thinking more of places like Mexico, India etc. And even there if you have the moolah you can likely get good care. The real advantage of first world countries is they have the facilities to ensure everyone, rich or poor, will be taken care of during emergencies, poor countries simply do no have the resources to do that. I am a bit (notice the word bit - I am no alarmist) worried about climate change, and think we need much better computer models (and much more powerful computers to run them on) to understand what's going on better. A real worry is the big emitters are all poor - they do not have the resources to do what may be necessary - somehow we need to change that not only for climate change but for outbreaks like this, That's why I am personally a fan of Bjorn Lomberg as is one of my heroes, Feynman's good friend - Freeman Dyson - the professor without even a PhD. Of course it goes without saying he could get the even higher award DSc anytime he wants simply by submitting a few papers of his voluminous work. I think Feynman was secretly jealous of that because he would have loved to say - hey buddy even I know that and I don't even have a PhD :woot::woot::woot::woot::woot::woot::woot::woot::woot::woot:. God I wish that man was still alive - he had the kind of mind valuable in crisis like this - he cut through 'crap' like a hot knife through butter. Not a lot of people know this but he also did research work in biology.

Thanks
Bill
 
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  • #60
bhobba said:
A real worry is the big emitters are all poor
The big emitters are (nearly) all rich. There is an extremely strong correlation between wealth and CO2 emissions. The big emitters just don't live in countries with a population of 1 billion, that's why the per country numbers are often smaller. Per capita is the only useful measure on the level of people: The average US or Australian citizen contributes as much to CO2 emissions as an Indian family of 8-9.
bhobba said:
The real advantage of first world countries is they have the facilities to ensure everyone, rich or poor, will be taken care of during emergencies, poor countries simply do no have the resources to do that.
In at least one of these first world countries many die because they don't go to a hospital unless it's a really life-threatening emergency (and then often to late to save them) - because they have to fear absurd hospital bills.

To contain such an outbreak the governments spend significant resources on isolation and treatment of the cases, luckily. No death in first world countries yet (~100 cases).
 
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  • #61
mfb said:
The big emitters are (nearly) all rich.

Yes I goofed and forgot abort the US and China. I should have said - India.

mfb said:
To contain such an outbreak the governments spend significant resources on isolation and treatment of the cases, luckily. No death in first world countries yet (~100 cases).

The US is an obvious anomaly here. They will spend resources on isolating and helping those they know about, but its dysfunctional medical system discourages many from seeking medical help so the system knows about them. I have said for a long time the US medical system is crazy. The silly thing is if it wasn't for vested interests it could be a lot better. But its not perfect here in Aus either. Get this one - normally, ie outside of hospital, X-Rays are free - the government reimburses the full cost, and they do not even charge the patient. But go into a private hospital and guess what - no reimbursement - you must pay and your insurance only partly covers it. I had to pay over $2000.00 just for x-rays and one MRI scan alone. And believe me they hit you for every little thing. When I left they gave me, without my consent, a diabetes kit with a packet of Jelly Beans to bring up sugar lows. I personally use honey for that. No asking or anything - check ring - $1.50 for what a chemist sells at 50 cents. Small change, but its maddening.

Thanks
Bill
 
  • #62
We are going geopolitical and semewhat anecdotal. Which is okay, but not in the Biology forum. Moving to General Discussion. :smile:
 
  • #63
Now a Nature report states that Remdesivir and the generic chloroquine are effective against nCoV.

https://www.nature.com/articles/s41422-020-0282-0

They are starting double blind trials in China so that the “effectiveness” can be scientifically demonstrated. If it works out, we will have two drugs already available on the market that can beat this thing! I’m starting to feel optimistic!

Expect results by sometime in April.

quoted from the report:

“Chloroquine is a cheap and a safe drug that has been used for more than 70 years and, therefore, it is potentially clinically applicable against the 2019-nCoV.”

The first US case was treated with Remdesivir after the patient began to develop pneumonia.

“at a period consistent with the development of radiographic pneumonia in this patient, clinicians pursued compassionate use of an investigational antiviral therapy. Treatment with intravenous remdesivir (a novel nucleotide analogue prodrug in development10,11) was initiated on the evening of day 7, and no adverse events were observed in association with the infusion. Vancomycin was discontinued on the evening of day 7, and cefepime was discontinued on the following day, after serial negative procalcitonin levels and negative nasal PCR testing for methicillin-resistant Staphylococcus aureus.

On hospital day 8 (illness day 12), the patient’s clinical condition improved...”

https://www.nejm.org/doi/full/10.1056/NEJMoa2001191?query=featured_home

This patient has since been discharged and has joined the ranks of the “cured.”
 
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  • #64
Thinking of chloroquinine triggered a distant memory of O-chem professor teaching us about the use of quinine to treat malaria. He had worked on a total synthesis for Sch###’s as a lower cost alternative to its cinchona bark natural source. He mentioned that quinine was used as the bittering agent in tonic water. So, googling antiviral activity of quinine gets me here:

https://www.sciencedirect.com/science/article/abs/pii/S0168170218302375

Quinine inhibits RNA reproduction against at least one virus.

Oh man! Could it be that perhaps maybe could be that gin and tonic could help cure nCoV? I can imagine a gin and tonic drip while going through this!😜
 
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  • #65
mfb said:
To contain such an outbreak the governments spend significant resources on isolation and treatment of the cases, luckily. No death in first world countries yet (~100cases).
Wait, let's learn some lessons here...is the quarantine area a problem? Why not use passenger vessels or cruise ships...then stationary on the shore?

https://www.cruiseindustrynews.com/...-for-14-days-10-positive-for-coronavirus.html
 
  • #66
It’s confusing - China imposed self lockdown on January 23 to prevent further spread of the virus and the rest of the world doing travel bans and quarantine measures - is this for real ? Am I missing something here ?

It’s quite difficult to explain to the public. We have travel ban but WHO says it’s wrong to impose such move ?

https://cnnphilippines.com/news/2020/2/6/World-Health-Organization-China-travel-ban-novel-coronavirus.html?fbclid=IwAR1-ZM_8lcjAANHrrFgaKK-gbJCAVb3fLL-rEbY9g4J-pO3F2TeAqnb4Iz4
 
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  • #67
kadiot said:
Wait, let's learn some lessons here...is the quarantine area a problem? Why not use passenger vessels or cruise ships...then stationary on the shore?

Top ten reasons not to use cruise ships as quarantine hospitals.

10. Being seasick on top of nCoV sick is NO FUN.
9. Who’s going to clean up THAT MESS?
8. The buffet isn’t allowed anymore.
7. The authorities aren’t willing to give command over to a captain.
6. A big ship like that is going to get in the way of commerce.
5. Need to book rooms at least two months in advance.
4. Nobody would ever use that ship again for travel while a popup hospital could be repurposed.
3. Hard to find workers willing to work at sea.
2. Bad optics for cruise ship operators.
1. That’s plan “B”
 
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  • #68
kadiot said:
It’s confusing - China imposed self lockdown on January 23 to prevent further spread of the virus and the rest of the world doing travel bans and quarantine measures - is this for real ? Am I missing something here ?

It’s quite difficult to explain to the public. We have travel van but WHO says it’s wrong to impose such move ?

https://cnnphilippines.com/news/2020/2/6/World-Health-Organization-China-travel-ban-novel-coronavirus.html?fbclid=IwAR1-ZM_8lcjAANHrrFgaKK-gbJCAVb3fLL-rEbY9g4J-pO3F2TeAqnb4Iz4

Research done on travel bans suggest that they could delay, but not stop the spread of pandemic diseases. For example, the WHO performed a meta-analysis on studies of past influenza outbreaks and concluded:

The results of our systematic review indicate that overall travel restrictions have only limited effectiveness in the prevention of influenza spread, particularly in those high transmissibility scenarios in which R0 is at least 1.9 (Box 2). The effect size varied according to the extent and timeliness of the restrictions, the size of the epidemic, strain transmissibility, the heterogeneity of the travel patterns, the geographical source and the urban density of international travel hubs. Only extensive travel restrictions – i.e. over 90% – had any meaningful effect on reducing the magnitude of epidemics. In isolation, travel restrictions might delay the spread and peak of pandemics by a few weeks or months but we found no evidence that they would contain influenza within a defined geographical area.
https://www.who.int/bulletin/volumes/92/12/14-135590/en/

While travel bans don't provide much benefit, there are a number of negatives associated with the imposition of travel bans:
Even if it were feasible to keep Coronavirus out through travel bans, these measures can make us less safe. Travel bans can penalize countries that report cases, which may in turn reduce countries’ willingness to share information about their outbreaks. Travel bans may also interrupt the flow of essential supplies upon which we depend to control the epidemic. China is a large producer of critical medicines and personal protective equipment — it is in our best interest to stay positively engaged with China in responding to this epidemic.
https://www.washingtonpost.com/outlook/2020/02/03/fighting-coronoavirus-with-travel-bans-is-mistake/

Travel bans can also restrict the flow of supplies and experts to sites of outbreaks, which can also harm efforts to contain epidemics.

Here's another news article that links to additional research on the topic: https://www.theglobeandmail.com/can...st-travel-bans-tied-to-coronavirus-backed-by/
 
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  • #69
Ygggdrasil said:
Research done on travel bans suggest that they could delay, but not stop the spread of pandemic diseases. For example, the WHO performed a meta-analysis on studies of past influenza outbreaks and concluded:https://www.who.int/bulletin/volumes/92/12/14-135590/en/
I wonder if there are other studies conducted on the same subject and came up with different findings.

Ygggdrasil said:
While travel bans don't provide much benefit, there are a number of negatives associated with the imposition of travel bans:

https://www.washingtonpost.com/outlook/2020/02/03/fighting-coronoavirus-with-travel-bans-is-mistake/

Travel bans can also restrict the flow of supplies and experts to sites of outbreaks, which can also harm efforts to contain epidemics.
Maybe they have own channel or usual transport for supplies and medical expert go in than back must self-quarantine.

Ygggdrasil said:
Here's another news article that links to additional research on the topic: https://www.theglobeandmail.com/can...st-travel-bans-tied-to-coronavirus-backed-by/
Only Canada followed the WHO's advice. The rest of the world does not agree. Approach is variable from country to country. I’d like to believe that worst case scenario is the best . It’s logical to stonewall a country. It’s basic.
 
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  • #70
Delaying the spread can come with benefits like a better availability of treatment options - and that way it might prevent an outbreak elsewhere.
 
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  • #71
chemisttree said:
Now a Nature report states that Remdesivir and the generic chloroquine are effective against nCoV.

I was, and still am, in no doubt modern science and commitment of all involved will basically hit this thing for a 6 - we have learned so much even in just the last few years eg UQ's new method of creating a vaccine ultra fast. Like what happened with Ebola we also have extremely committed people willing to even put their own life on the line - we have the tools and the courage.

Thanks
Bill
 
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  • #72
Fact-check please:

"Good news! The registration for clinical trials on the antiviral drug Remdesivir has been approved, and the first batch of pneumonia patients infected by the novel Coronavirus are expected to start taking the drug Thursday"http://www.xinhuanet.com/english/2020-02/06/c_138758836.htm
 
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  • #73
kadiot said:
Fact-check please:

"Good news! The registration for clinical trials on the antiviral drug Remdesivir has been approved, and the first batch of pneumonia patients infected by the novel Coronavirus are expected to start taking the drug Thursday"

Still waiting to see if they will do the same for chloroquine.
 
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  • #74
chemisttree said:
There is no possible way to compare those two numbers to nCoV. Not a good idea to compare time series data to final counts. China started building two special hospitals when the official case count was in the low thousands! If the infection rates were accurate, how come a city like Wuhan with available hospital bedspace of greater than 40,000 is swamped by the then number of around 2,000?

View the time series data here:
https://ncov.r6.no/

Looks to me like nCoV is much worse than SARS.

There is substantial uncertainty right now. It is by no means clear that the reporting is accurate for any of the numbers.

When people die at home, it is not clear that they are tested. So the deaths might be significantly under reported. At the same time, it seems that some people when infected have quite mild symptoms. So the infected rate could be significantly under reported. So the mortality rate could be quite drastically high or low.

Regarding the website linked here. At the bottom is a graph showing infections and deaths broken between all of China, and China excluding Hubei (the province where Wuhan is). The deaths outside Hubei were reported as 75 on Day 24, and 11 on Day 25. What's that? Did 64 people mistakenly get declared dead? Or their location on death mistaken? What's up with that?
 
  • #75
File under, “No Good Deed.” China has filed a patent against Gilead’s patented Remdesivir anti-viral medication for use in treating nCoV. The Wuhan Institute claims to have made the application out of “national interest” and won’t exercise their patent rights if foreign pharmaceutical firms work with China to curb the contagion. In other words, “let us make it in China license-free or we’re just going to steal it from you!”

What an outrage!
https://time.com/5778216/china-patent-coronavirus-drug/
 
  • #76
chemisttree said:
File under, “No Good Deed.” China has filed a patent against Gilead’s patented Remdesivir anti-viral medication for use in treating nCoV. The Wuhan Institute claims to have made the application out of “national interest” and won’t exercise their patent rights if foreign pharmaceutical firms work with China to curb the contagion. In other words, “let us make it in China license-free or we’re just going to steal it from you!”

What an outrage!
https://time.com/5778216/china-patent-coronavirus-drug/
They are just into intellectual property. What is wrong with documenting what you know? It does not take your time from the curing? If America did it, we see nothing wrong with it.
 
  • #77
chemisttree said:
File under, “No Good Deed.” China has filed a patent against Gilead’s patented Remdesivir anti-viral medication for use in treating nCoV. The Wuhan Institute claims to have made the application out of “national interest” and won’t exercise their patent rights if foreign pharmaceutical firms work with China to curb the contagion. In other words, “let us make it in China license-free or we’re just going to steal it from you!”

What an outrage!
https://time.com/5778216/china-patent-coronavirus-drug/

That article does not best describe this situation. WTO rules gives China the right to declare an emergency and compel a company to license a patent to protect the public. China would then be required to pay a fair market value license fee, so they are not 'stealing' it.

The Chinese Government is quarantining 60-odd million people in Hubei province to try and slow the spread of nCoV for everyone's benefit so your 'no good deed' sentiment seems to me uncharitable.
 
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  • #78
Tghu Verd said:
That article does not best describe this situation. WTO rules gives China the right to declare an emergency and compel a company to license a patent to protect the public. China would then be required to pay a fair market value license fee, so they are not 'stealing' it.

The Chinese Government is quarantining 60-odd million people in Hubei province to try and slow the spread of nCoV for everyone's benefit so your 'no good deed' sentiment seems to me uncharitable.
If they weren’t stealing it then they could just operate under WTO rules and declare the emergency as you have mentioned. They have not chosen that path and are instead patenting it in China. Patenting on top of another patent, one which specifically identifies the Coronavirus family for applicability, is stealing the patent. Providing your valuable intellectual property that has cost your company many many millions of dollars at no cost (very charitable) only to have the patent stolen for “national interest” certainly qualifies as accurate and the action by the Chinese authorities is most certainly not charitable. It IS an outrage.
 
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  • #79
kadiot said:
They are just into intellectual property. What is wrong with documenting what you know? It does not take your time from the curing? If America did it, we see nothing wrong with it.
This is way beyond “documenting what you know.” The first patient in the US was treated with Remdesivir, successfully, after all. If someone in America tried to patent a claim in some else’s foreign patent only because they proved it to be true in a case they identified, it would be denied as would be expected. When has “America” done this? You know of a case?
 
  • #80
chemisttree said:
File under, “No Good Deed.” China has filed a patent against Gilead’s patented Remdesivir anti-viral medication for use in treating nCoV. The Wuhan Institute claims to have made the application out of “national interest” and won’t exercise their patent rights if foreign pharmaceutical firms work with China to curb the contagion. In other words, “let us make it in China license-free or we’re just going to steal it from you!”

What an outrage!
https://time.com/5778216/china-patent-coronavirus-drug/

It's worth being a bit more precise with the claims here. "China" did not apply for the patent, the Wuhan Institute of Virology did. Your claim is akin to saying that actions by, say the University of Wisconsin, represents the position of the US govnerment.

Furthermore, anyone can file a patent and make any claims they want. The real test is whether the Chinese government grants the patent. Other sources are skeptical whether the Chinese government will grant the patent to the Wuhan Institute of Virology:

As there is significant prior art (e.g., Gilead’s own patent applications including CN108348526A entitled “Methods for treating arenaviridae and coronaviridae virus infections”) it is unclear if the China National Intellectual Property Administration will grant a patent.
https://www.natlawreview.com/article/wuhan-institute-virology-applies-patent-gilead-s-remdesivir
 
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  • #81
Ygggdrasil said:
It's worth being a bit more precise with the claims here. "China" did not apply for the patent, the Wuhan Institute of Virology did. Your claim is akin to saying that actions by, say the University of Wisconsin, represents the position of the US govnerment.
Except that in this case it does. Wuhan Institute of Virolology is not some independent local think tank, its actually called Wuhan Institute of Virolology, Chinese Academy of Sciences. It is most certainly the Chinese government’s Academy and referring to it as “China” is as accurate as it gets.

https://www.loc.gov/item/lcwaN0003010/
 
  • #82
chemisttree said:
It IS an outrage

I am not going to deny your right to feelings of outrage, @chemisttree. I just don't share it in this case.

If you're a history buff, you might find the idea of China (or its proxy) snaffling US IP very ironic. Peter Andreas chronicles the US Government's wholesale IP theft in his book “Smuggler Nation: How Illicit Trade Made America”, though back then - the late 18th and early 19th centuries - the main victim was Britain.

Clearly, times change, but I have no doubt that if a foreign company had IP that would help America in a crisis such as this, it would be appropriated without a second thought, esp, if that might save thousands. This is clearly a hypothetical question, but I am interested in whether you would feel outrage in such circumstances.
 
  • #83
chemisttree said:
...The first patient in the US was treated with Remdesivir, successfully...
Weird, if it was successful, that Gilead's stock price budged, almost imperceptibly.

Screen Shot 2020-02-07 at 3.33.06 PM.png


Am I missing something here?

ps. I find it funny that "GILD", Gilead's stock ticker tag, means "gold". (etymologically, anyways)
Imagine having the patent on the only defense against something potentially deadly affecting billions of people.
Cha-Ching!
 
  • #84
OmCheeto said:
Weird, if it was successful, that Gilead's stock price budged, almost imperceptibly.

View attachment 256781

Am I missing something here?
VERY unusual that Gilead is almost unique in its non-performance. The Chinese Central Bank has been injecting massive amounts of cash into their market and markets around the world have been rocked by... record highs? I also wonder, “why not Gilead too?”
 
  • #85
Tghu Verd said:
...but I have no doubt that if a foreign company had IP that would help America in a crisis such as this, it would be appropriated without a second thought, esp, if that might save thousands. This is clearly a hypothetical question, but I am interested in whether you would feel outrage in such circumstances.
Of course I would. Do you have any modern examples of a US governmental academy, Department, representative doing something like this for reasons of “National Interest?” For any reason? I mean without going all the way back to the late 1700’s.

If you’re not a history buff, it would be worthwhile to remember the times back them. Britain had just lost a bitterly-fought war and was capitalizing on its immense seapower, seizing US flagged ships and cargo on the high seas bound for France and enslaving (they called it “impressment”) the crew. There was no WTO, no global economy, no cooperation between major powers for IP rights and on and on... And it (impressment) caused a war, of course. I’m not surprised that in that environment that IP theft against Britain was rampant. But if it were to happen today I would be outraged.
 
  • #86
chemisttree said:
Of course I would. Do you have any modern examples of a US governmental academy, Department, representative doing something like this for reasons of “National Interest?” For any reason? I mean without going all the way back to the late 1700’s.
Rocket technology after WW II, rocket technology during the cold war?
The US government continues to spy on everyone and everything, and it is quite obvious that this information is used. More recent specific examples are rarely known publicly for obvious reasons.
 
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  • #87
A Royal Caribbean cruise ship was detained in a NJ port while the CDC screened 27 passengers who recently traveled from China. A family of 4 was hospitalized; one family member tested positive for the (regular) flu.

The ship has been cleared but still Royal Caribbean and Nowegian Cruises have banned anyone with a Chinese, Hong Kong, or Macao passport. Yikes! This is getting serious!
 
  • #88
mfb said:
Rocket technology after WW II, rocket technology during the cold war?
I’m all ears. What rocket technology? Paperclip?
Paperclip was spoils of a war declared on the US by Germany.
 
  • #89
Oh great, you found a new label for it. I'm sure you'll also find a new label for Russian rocket technology used by the US. Okay... pointless to continue this discussion.
 
  • #90
chemisttree said:
Of course I would.

I hoped for such, but assumptions must be tested.

In terms of the OP, IP theft is lurching us off-topic, but it happens daily, everywhere. Just a few domestic examples include Anthony Levandowski being charged with 33 counts of theft and attempted theft of trade secrets from Google, Zillow Group filing an IP infringement suit against competitor Urban Compass, and Apple purportedly having stolen IP related to their Watch tech.

In terms of your specific question, I'd say the NSA qualifies as a US government agency that has knowingly violated intellectual property rights over an extended period, and numerous small businesses accused the Government of stealing their IP seven or so years ago. The CLOUD Act has been cited by EU members as a mechanism for the US Government to engage in espionage, though I don't feel it has been set up for that purpose and it probably is a blunt instrument for such.

Sadly, theft seems to form part of the human condition, but if mitigating circumstances ever apply, surely the situation that triggered this whole discussion is an example.
 
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  • #91
For mobile phones, something like that exists. But there are too many different 'cable' instruments/systems so I doubt that any uniform solution would exist/would be useful.

But this seems to be a bit off-topic, unless you further elaborate its relation to the discussed situation?
 
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  • #92
Let us stay with Wuhan Coronavirus.

Further digressions will have an extremely short half-life. :oldgrumpy: We have had too many. The topic is important. The NSA and citizen band radio are not germane to the topic. Therefore: Start separate threads please.

Thanks
 
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  • #93
Interview with a doctor on the front lines
‘In the segregated ward, we wear level-3 protective gear. One shift is 12 hours for a doctor and eight hours for a nurse. Since protective gear is in a shortage, there is only one set for a medical staff member a day. We refrain from eating or drinking during our shift because the gear is no longer protective once we go to the washroom.’

‘The most regretful thing to me was a pregnant woman from Huanggang. She was in very serious condition. Nearly 200,000 yuan (S$39,505) was spent after more than a week in the ICU. She was from the countryside, and the money for hospitalisation was borrowed from her relatives and friends. Her condition was improving after the use of Ecmo, and she was likely to survive. But her husband decided to give up. He cried for his decision. I wept too because I felt there was hope for her to be saved. The woman died after we gave up. And exactly the next day, the government announced a new policy that offers free treatment for all coronavirus-infected patients. I feel so sorry for that pregnant woman.

https://www.straitstimes.com/asia/e...ook-life-and-death-in-a-wuhan-coronavirus-icu
 
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Likes kadiot, jim mcnamara, Klystron and 1 other person
  • #97
kadiot said:
"It is probable that the virus originated in bats, with pangolins being the vector into humans. In past epidemics, vectors have been pigs, chickens, ducks and camels."

Taken from:

https://www.dailymaverick.co.za/art...n3zlXCxcw_kTkyVD6d9okpEaOO7ZXGKOwWrvCD4YtcRaI
If true then how did a pangolin catch it from a bat? Are pangolins eating dead bats or do they feed on bat feces?
Or is this someone trying to stop the chinese from killing this endangered species by scaring them with this plague? What’s next?

Rhino horn?
 
  • #98
What? Me worry?

So I go to my neighborhood big box supermarket/clothing/pharmacy/sporting goods/outdoor/automotive/electronics/shoe/bank/nail salon/McDonalds store... I’m sure you know the type, to get some stuff. Just to check on how people in San Antonio might be reacting to the Wuhan flu, I check out the pharmacy to try and find hand sanitizer.

S’gone! Adios! Sold out!

It begins😕. A quarantine plane landed in SA on Friday, so that might be the reason.

Oh well! Here’s how to make it:

you will need:
43 mL 70% isopropyl (still available!)
0.5 g Carbopol 940
0.38 mL Triethanolamine
~7 mL DI water

Add 43 mL of isopropanol to a small cup and slowly add the powdered Carbapol 940 with stirring. Continue stirring to completely suspend the polymer. It may take 10-15 minutes. Continue stirring and add the triethanolamine dropwise with a small syringe (no needle required). Stir until triethanolamine is uniformly mixed. Add water and stir until uniformly mixed.

There you have it. 50 mL of hand sanitizer! A lot of work for only 2 ounces so you should probably scale up a bit. I’d better not see you selling this stuff on ebay!

Oh, I totally plagiarized this recipe. Hat tip to Patrick Pham.


If you want to use ethanol instead of isopropyl alcohol you will need to get some Everclear (95% ethanol) or some USP grade. Don’t use denatured ethanol since it might contain something not good for hands like jet fuel or something (darn revenuers!). If you use Everclear, use 32 mL ethanol and 18 mL of water. I don’t think Vodka is strong enough.
 
Last edited:
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  • #99
Whats new in this confirmation. Arent all Coronavirus airborned like the common colds?

https://www.news.com.au/lifestyle/health/health-problems/coronavirus-is-airborne-chinese-official-confirms/news-story/201218c04deb601b1b144f4cbbc4d807#.m4qig
"
It comes as a Chinese official confirmed a worrying new fact about the deadly coronavirus; infections are taking place through aerosol transmission.

It was previously understood that two main ways the virus transmitted from person to person were:

• Direct transmission: breathing in air close to an infected patient who sneezes or coughs, and

• Contact transmission: when a person touches an object tainted with the virus before infecting themselves by touching their mouth, nose or eyes.

However, over the weekend, an official in Shanghai confirmed the virus also traveled through aerosol transmission, which means it can float a long distance through the air and cause infection later when it is breathed in.

“Aerosol transmission refers to the mixing of the virus with droplets in the air to form aerosols, which causes infection after inhalation, according to medical experts,” Shanghai Civil Affairs Bureau deputy head Zeng Qun said at press briefing on Saturday, the China Daily reports."
 
  • #100
chirhone said:
Whats new in this confirmation. Arent all Coronavirus airborned like the common colds?

https://www.news.com.au/lifestyle/health/health-problems/coronavirus-is-airborne-chinese-official-confirms/news-story/201218c04deb601b1b144f4cbbc4d807#.m4qig
"
It comes as a Chinese official confirmed a worrying new fact about the deadly coronavirus; infections are taking place through aerosol transmission.

It was previously understood that two main ways the virus transmitted from person to person were:

• Direct transmission: breathing in air close to an infected patient who sneezes or coughs, and

• Contact transmission: when a person touches an object tainted with the virus before infecting themselves by touching their mouth, nose or eyes.

However, over the weekend, an official in Shanghai confirmed the virus also traveled through aerosol transmission, which means it can float a long distance through the air and cause infection later when it is breathed in.

“Aerosol transmission refers to the mixing of the virus with droplets in the air to form aerosols, which causes infection after inhalation, according to medical experts,” Shanghai Civil Affairs Bureau deputy head Zeng Qun said at press briefing on Saturday, the China Daily reports."
Droplet - respiratory secretions can travel 3-6 feet away due to generation of aerosols when one sneezes or coughs. Since the droplets are relatively large, they don't stay in the air very long.

Airborne (technical term) - transmission via tiny aerosolized respiratory secretions that can stay in the air like smoke for sustained periods of time. There are very few diseases that need airborne precautions: tuberculosis, measles and chicken pox are the classic ones.

Hence, aerosol is NOT always equal to airborne (in the strict sense) because if the particles are large, they can just be droplet transmission. If you use "airborne" as an adjective and not as a strict technical term, then it becomes even more confusing.
 

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