COVID US-Japan COVID R.1 Variant: What To Know

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SUMMARY

The US-Japan COVID R.1 variant has emerged but is not classified as a variant of concern (VOC) due to its low occurrence compared to variants like alpha and delta. Vaccines such as Johnson & Johnson, Sputnik V, Pfizer, and Moderna remain effective against R.1. The discussion highlights the importance of understanding spike protein mutations and their implications for vaccine efficacy. Tools like Nextstrain are essential for analyzing the genetic diversity of SARS-CoV-2 variants.

PREREQUISITES
  • Understanding of SARS-CoV-2 spike protein mutations
  • Familiarity with COVID-19 vaccine types and their efficacy
  • Knowledge of variant classification, specifically VOCs
  • Experience with genomic analysis tools like Nextstrain
NEXT STEPS
  • Research the implications of spike protein mutations on vaccine efficacy
  • Explore the Nextstrain platform for real-time genomic epidemiology
  • Study the CDC's findings on COVID variant classifications
  • Investigate the impact of COVID-19 variants on public health policies
USEFUL FOR

This discussion is beneficial for epidemiologists, public health officials, vaccine researchers, and anyone involved in monitoring COVID-19 variants and their implications for vaccination strategies.

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Forbes BTW seems to actively support COVID vaccine use and efficacy. Your article tries to explain the important spike amino acid changes in the spike protein since December 2019. Mutations if you like, and the degree to which they get past vaccinations.

The whole idea is that someday one of the beasties will truly evade the current vaccine team: J&J, Sputnik V, Pfizer, Moderna, etc. COVID diversity is increasing:

This tangled mess shows what is meant by diversity - the family tree. It takes special software to make sense of the data behind the graphic. Nextstrain has links to some of that.

https://nextstrain.org/ncov/open/globalR.1 from the CDC:
https://www.cdc.gov/mmwr/volumes/70/wr/mm7017e2.htm

The MMRW article is primarily about a new variant R.1 in the context of vaccination efficacy for new COVID viruses.

R.1 not classified as a VOC - variant of concern. Why? The highest level of occurrence is really low, compared to alpha or delta. Vaccines meant for other COVID flavors worked well against R.1

Given the fact that it emerged at about the time the delta variant became a dominant VOC, R.1 - so far - has not taken off in any of the susceptible populations.
 

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