Difference between fibrous proteins and globular proteins

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SUMMARY

The discussion clarifies the fundamental differences between fibrous proteins and globular proteins. Fibrous proteins are characterized by their elongated shape and are generally insoluble, possessing only primary and secondary structures. In contrast, globular proteins have a spheroidal shape, are soluble, and contain primary, secondary, tertiary, and sometimes quaternary structures. The primary structure refers specifically to the linear sequence of amino acids in all proteins.

PREREQUISITES
  • Understanding of protein structure terminology (primary, secondary, tertiary, quaternary)
  • Basic knowledge of amino acids and their sequences
  • Familiarity with protein solubility concepts
  • Knowledge of the differences in protein shapes (elongated vs. spheroidal)
NEXT STEPS
  • Research the role of primary structure in protein function
  • Study the significance of tertiary and quaternary structures in globular proteins
  • Explore examples of fibrous proteins and their biological functions
  • Investigate methods for determining protein solubility and structure
USEFUL FOR

Students in biochemistry, molecular biology researchers, and anyone interested in the structural biology of proteins.

littlelady
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Hey guys, can somebody helps me to understand better about fibrous vs globular protein please

"So what is the main difference between fibrous proteins and globular proteins? Aside from the difference in shape (elongated vs. spheroidal) and solubility (insoluble vs. soluble), fibrous proteins generally have only primary and secondary structure whereas globular proteins have tertiary and sometimes quaternary structure in addition to primary and secondary structure."

My question is

Fibrous only posses primary and secondary strure
Globular only posses tertiary and quanternary structure right? and also primary and secondary?? ?

I read the pagra above from online but confusing...i THINK primary stuture is only sequence of amino acid..it doesn't have spherical shape...
 
Last edited:
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littlelady said:
i THINK primary stuture is only sequence of amino acid..it doesn't have spherical shape...
Correct, primary structure refers to the amino acid sequence, and is present for every protein.
 
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