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Effectiveness of early COVID-19 treatments
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[QUOTE="Ygggdrasil, post: 6316306, member: 124113"] The high mortality of COVID-19 patients on ventilators seems like an outlier. Here's a [URL='https://ccforum.biomedcentral.com/articles/10.1186/cc10369']study [/URL]of 178 H1N1 cases from 2009, which shows a 46% mortality of patients on mechanical ventilation, and a wider [URL='https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2740069']meta-analysis [/URL]of treatments for ARDS (acute respiratory distress syndrome) finds a 34.6% mortality of patients with severe ARDS treated with mechanical ventilation or ECMO, so ventilators are clearly helping in these situations. If I were to speculate (again, disclaimer that I am not a medical doctor nor do I have any particular expertise in medical science aside from skimming through a few of these papers), I would guess that there could be two reasons for the very high mortality of COVID-19 patients on ventilators: 1) Ventilators treat the symptoms but not the cause of the problems. If the virus is still active in the body, ventilators ultimately won't solve that problem. This would suggest that ventilators could become more effective if effective anti-viral treatments are found that can address the underlying viral infection. 2) It has been [URL='https://www.nytimes.com/article/coronavirus-body-symptoms.html']reported [/URL]that the virus could infect other organs of the body, so while ventilation could solve issues with lung function, the virus may cause death due to damage to other organs such as the heart, liver or kidneys. [/QUOTE]
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