A siphon cannot function in a vacuum because the pressure must decrease with height to create the necessary upward force against gravity, and liquids cannot withstand negative pressures. While surface tension and intermolecular forces play a role in siphoning, they are not sufficient to overcome the limitations imposed by atmospheric pressure. The discussion highlights that even if a siphon is initiated, factors like vapor pressure can lead to vapor-lock, preventing continued flow. Additionally, while some liquids, like superfluids, can exhibit siphoning behavior without traditional mechanisms, this is not applicable to standard siphoning principles. Ultimately, the key to siphoning is maintaining a pressure difference, which requires the source to be at a higher elevation than the sink.